上颌骨口腔无色素性黑色素瘤

Oral amelanotic melanoma of the maxilla.

作者信息

Saghravanian Nasrollah, Pazouki Mahdi, Zamanzadeh Maryam

机构信息

Associated Professor, Department of Oromaxillofacial Pathologist, Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mash-had University of Medical Sciences, Mashhad, Iran.

Oral and Maxillofacial Pathologist, Mashhad, Iran.

出版信息

J Dent (Tehran). 2014 Nov;11(6):721-5. Epub 2014 Nov 30.

PMID:25628704

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4281196/

Abstract

Amelanotic melanoma is a variant of malignant melanoma comprising 2% to 8% of all malignant melanomas. The amelanotic presentation of melanoma in the oral cavity is extremely rare and has been reported only occasionally in the literature. Moreover, the lack of melanin makes these tumors difficult to diagnose than that of pigmented lesions and the prognosis tends to be poorer. Herein, we report an amelanotic melanoma involving the oral mucosa of the maxilla in a 27 year-old male.

摘要

无色素性黑色素瘤是恶性黑色素瘤的一种变体，占所有恶性黑色素瘤的2%至8%。口腔内黑色素瘤的无色素表现极为罕见，文献中仅有偶尔报道。此外，缺乏黑色素使得这些肿瘤比色素沉着性病变更难诊断，且预后往往更差。在此，我们报告一例发生于一名27岁男性上颌口腔黏膜的无色素性黑色素瘤。