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外科异体面部重建:面部移植

Surgical-allogeneic facial reconstruction: facial transplants.

作者信息

Goiato Marcelo Coelho, Dos Santos Daniela Micheline, Bannwart Lisiane Cristina, Haddad Marcela Filié, Pereira Leonardo Viana, Filho Aljomar José Vechiato

机构信息

Professor, Oral Oncology Center, Araçatuba School of Dentistry, University Estadual Paulista-UNESP, São Paulo, Brazil Student, Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, Univ Estadual Paulista-UNESP, São Paulo, Brazil.

Student, Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, Univ Estadual Paulista-UNESP, São Paulo, Brazil.

出版信息

J Dent (Tehran). 2014 Nov;11(6):733-9. Epub 2014 Nov 30.

PMID:25628706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4281198/
Abstract

Several factors including cancer, malformations and traumas may cause large facial mutilation. These functional and aesthetic deformities negatively affect the psychological perspectives and quality of life of the mutilated patient. Conventional treatments are prone to fail aesthetically and functionally. The recent introduction of the composite tissue allotransplantation (CTA), which uses transplanted facial tissues of healthy donors to recover the damaged or non-existent facial tissue of mutilated patients, resulted in greater clinical results. Therefore, the present study aims to conduct a literature review on the relevance and effectiveness of facial transplants in mutilated subjects. It was observed that the facial transplants recovered both the aesthetics and function of these patients and consequently improved their quality of life.

摘要

包括癌症、畸形和创伤在内的多种因素可能导致严重的面部毁损。这些功能和美学上的畸形会对面部毁损患者的心理状态和生活质量产生负面影响。传统治疗方法在美学和功能方面往往容易失败。最近引入的复合组织异体移植(CTA),即使用健康供体的面部组织移植来修复面部毁损患者受损或缺失的面部组织,取得了更好的临床效果。因此,本研究旨在对面部移植在面部毁损患者中的相关性和有效性进行文献综述。研究发现,面部移植恢复了这些患者的美学和功能,从而改善了他们的生活质量。

相似文献

1
Surgical-allogeneic facial reconstruction: facial transplants.外科异体面部重建:面部移植
J Dent (Tehran). 2014 Nov;11(6):733-9. Epub 2014 Nov 30.
2
First Russian Experience of Composite Facial Tissue Allotransplantation.俄罗斯首例复合面部组织同种异体移植经验。
Plast Reconstr Surg Glob Open. 2019 Nov 21;7(11):e2521. doi: 10.1097/GOX.0000000000002521. eCollection 2019 Nov.
3
Measuring utilities of severe facial disfigurement and composite tissue allotransplantation of the face in patients with severe face and neck burns from the perspectives of the general public, medical experts and patients.从普通公众、医学专家和患者的角度衡量严重面部毁容和面部复合组织同种异体移植的效用,这些患者患有严重的面颈部烧伤。
Burns. 2015 Nov;41(7):1524-31. doi: 10.1016/j.burns.2015.05.002. Epub 2015 Jun 9.
4
[Review on progress of facial allotransplantation].[面部同种异体移植研究进展综述]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2006 Dec;20(12):1262-5.
5
Craniomaxillofacial trauma management in austere and war zone environments - A role for composite tissue allotransplantation?在严峻和战区环境中的颅颌面创伤管理——复合组织同种异体移植能发挥作用吗?
Ann Burns Fire Disasters. 2019 Dec 31;32(4):308-320.
6
Facial Transplantation.面部移植
Facial Plast Surg Clin North Am. 2016 Aug;24(3):367-77. doi: 10.1016/j.fsc.2016.03.013.
7
Vascularized composite allotransplantation and tissue engineering.血管化复合组织异体移植与组织工程
J Craniofac Surg. 2013 Jan;24(1):256-63. doi: 10.1097/SCS.0b013e318275f173.
8
Complex facial reconstruction by vascularized composite allotransplantation: the first Belgian case.通过血管化复合组织异体移植进行复杂面部重建:比利时首例病例。
J Plast Reconstr Aesthet Surg. 2015 Mar;68(3):362-71. doi: 10.1016/j.bjps.2014.11.005. Epub 2014 Nov 20.
9
[Face allotransplantation: anatomical study, potential partial and total facial allografts harvesting and clinical application].[面部同种异体移植:解剖学研究、潜在的部分及全脸同种异体移植物获取与临床应用]
Ann Chir Plast Esthet. 2007 Oct;52(5):485-93. doi: 10.1016/j.anplas.2007.06.003. Epub 2007 Aug 20.
10
Facial transplantation: history and update.面部移植:历史与最新进展
Acta Chir Belg. 2015 Mar-Apr;115(2):99-103. doi: 10.1080/00015458.2015.11681077.

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[Tumors of the paranasal sinus invading the orbit].[侵犯眼眶的鼻窦肿瘤]
HNO. 2018 Oct;66(10):730-742. doi: 10.1007/s00106-018-0540-3.
2
Evaluation of Patients' Satisfaction after Class III Orthognathic Surgery.正颌外科III类手术后患者满意度评估
J Clin Diagn Res. 2015 Oct;9(10):ZC23-7. doi: 10.7860/JCDR/2015/14633.6587. Epub 2015 Oct 1.

本文引用的文献

1
Logistics and strategy of multiorgan procurement involving total face allograft.涉及全颜面同种异体移植的多器官获取的物流和策略。
Am J Transplant. 2011 May;11(5):1091-7. doi: 10.1111/j.1600-6143.2011.03489.x. Epub 2011 Mar 28.
2
Patients' satisfaction after surgical facial reconstruction or after rehabilitation with maxillofacial prosthesis.
J Craniofac Surg. 2011 Mar;22(2):766-9. doi: 10.1097/SCS.0b013e318207f302.
3
Restoration of facial form and function after severe disfigurement from burn injury by a composite facial allograft.复合异体面部移植修复严重烧伤所致毁容后面部形态和功能。
Am J Transplant. 2011 Feb;11(2):386-93. doi: 10.1111/j.1600-6143.2010.03368.x. Epub 2011 Jan 7.
4
Clinical considerations in face transplantation.面部移植的临床考虑。
Burns. 2010 Nov;36(7):951-8. doi: 10.1016/j.burns.2010.01.011. Epub 2010 Apr 21.
5
Psychosocial considerations in facial transplantation.面部移植中的社会心理考虑因素。
Burns. 2010 Nov;36(7):959-64. doi: 10.1016/j.burns.2010.01.012. Epub 2010 Apr 7.
6
Most frequent tumors in maxillofacial area rehabilitated through surgical reconstruction and prostheses.
J Craniofac Surg. 2010 Mar;21(2):396-9. doi: 10.1097/SCS.0b013e3181cfa70c.
7
Arguing the ethics of facial transplantation.
Arch Facial Plast Surg. 2010 Jan-Feb;12(1):60-3. doi: 10.1001/archfacial.2009.106.
8
Composite tissue allotransplantation.复合组织同种异体移植。
Plast Reconstr Surg. 2009 Dec;124(6 Suppl):e327-e339. doi: 10.1097/PRS.0b013e3181bf8413.
9
The world's experience with facial transplantation: what have we learned thus far?全球面部移植的经验:到目前为止我们学到了什么?
Ann Plast Surg. 2009 Nov;63(5):572-8. doi: 10.1097/SAP.0b013e3181ba5245.
10
Near-total human face transplantation for a severely disfigured patient in the USA.美国为一名严重毁容患者进行了近乎全脸移植手术。
Lancet. 2009 Jul 18;374(9685):203-9. doi: 10.1016/S0140-6736(09)61155-7. Epub 2009 Jul 14.