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外科异体面部重建:面部移植

Surgical-allogeneic facial reconstruction: facial transplants.

作者信息

Goiato Marcelo Coelho, Dos Santos Daniela Micheline, Bannwart Lisiane Cristina, Haddad Marcela Filié, Pereira Leonardo Viana, Filho Aljomar José Vechiato

机构信息

Professor, Oral Oncology Center, Araçatuba School of Dentistry, University Estadual Paulista-UNESP, São Paulo, Brazil Student, Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, Univ Estadual Paulista-UNESP, São Paulo, Brazil.

Student, Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, Univ Estadual Paulista-UNESP, São Paulo, Brazil.

出版信息

J Dent (Tehran). 2014 Nov;11(6):733-9. Epub 2014 Nov 30.

Abstract

Several factors including cancer, malformations and traumas may cause large facial mutilation. These functional and aesthetic deformities negatively affect the psychological perspectives and quality of life of the mutilated patient. Conventional treatments are prone to fail aesthetically and functionally. The recent introduction of the composite tissue allotransplantation (CTA), which uses transplanted facial tissues of healthy donors to recover the damaged or non-existent facial tissue of mutilated patients, resulted in greater clinical results. Therefore, the present study aims to conduct a literature review on the relevance and effectiveness of facial transplants in mutilated subjects. It was observed that the facial transplants recovered both the aesthetics and function of these patients and consequently improved their quality of life.

摘要

包括癌症、畸形和创伤在内的多种因素可能导致严重的面部毁损。这些功能和美学上的畸形会对面部毁损患者的心理状态和生活质量产生负面影响。传统治疗方法在美学和功能方面往往容易失败。最近引入的复合组织异体移植(CTA),即使用健康供体的面部组织移植来修复面部毁损患者受损或缺失的面部组织,取得了更好的临床效果。因此,本研究旨在对面部移植在面部毁损患者中的相关性和有效性进行文献综述。研究发现,面部移植恢复了这些患者的美学和功能,从而改善了他们的生活质量。

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本文引用的文献

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Clinical considerations in face transplantation.面部移植的临床考虑。
Burns. 2010 Nov;36(7):951-8. doi: 10.1016/j.burns.2010.01.011. Epub 2010 Apr 21.
5
Psychosocial considerations in facial transplantation.面部移植中的社会心理考虑因素。
Burns. 2010 Nov;36(7):959-64. doi: 10.1016/j.burns.2010.01.012. Epub 2010 Apr 7.
6
Most frequent tumors in maxillofacial area rehabilitated through surgical reconstruction and prostheses.
J Craniofac Surg. 2010 Mar;21(2):396-9. doi: 10.1097/SCS.0b013e3181cfa70c.
7
Arguing the ethics of facial transplantation.
Arch Facial Plast Surg. 2010 Jan-Feb;12(1):60-3. doi: 10.1001/archfacial.2009.106.
8
Composite tissue allotransplantation.复合组织同种异体移植。
Plast Reconstr Surg. 2009 Dec;124(6 Suppl):e327-e339. doi: 10.1097/PRS.0b013e3181bf8413.

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