Gross Anita, Kay Theresa M, Paquin Jean-Philippe, Blanchette Samuel, Lalonde Patrick, Christie Trevor, Dupont Genevieve, Graham Nadine, Burnie Stephen J, Gelley Geoff, Goldsmith Charles H, Forget Mario, Hoving Jan L, Brønfort Gert, Santaguida Pasqualina L
School of Rehabilitation Science & Department of Clinical Epidemiology and Biostatistics, McMaster University, 1400 Main Street West, Hamilton, ON, Canada, L8S 1C7.
Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD004250. doi: 10.1002/14651858.CD004250.pub5.
Neck pain is common, disabling and costly. Exercise is one treatment approach.
To assess the effectiveness of exercises to improve pain, disability, function, patient satisfaction, quality of life and global perceived effect in adults with neck pain.
We searched MEDLINE, MANTIS, ClinicalTrials.gov and three other computerized databases up to between January and May 2014 plus additional sources (reference checking, citation searching, contact with authors).
We included randomized controlled trials (RCTs) comparing single therapeutic exercise with a control for adults suffering from neck pain with or without cervicogenic headache or radiculopathy.
Two review authors independently conducted trial selection, data extraction, 'Risk of bias' assessment and clinical relevance. The quality of the evidence was assessed using GRADE. Meta-analyses were performed for relative risk and standardized mean differences (SMD) with 95% confidence intervals (CIs) after judging clinical and statistical heterogeneity.
Twenty-seven trials (2485 analyzed /3005 randomized participants) met our inclusion criteria.For acute neck pain only, no evidence was found.For chronic neck pain, moderate quality evidence supports 1) cervico-scapulothoracic and upper extremity strength training to improve pain of a moderate to large amount immediately post treatment [pooled SMD (SMDp) -0.71 (95% CI: -1.33 to -0.10)] and at short-term follow-up; 2) scapulothoracic and upper extremity endurance training for slight beneficial effect on pain at immediate post treatment and short-term follow-up; 3) combined cervical, shoulder and scapulothoracic strengthening and stretching exercises varied from a small to large magnitude of beneficial effect on pain at immediate post treatment [SMDp -0.33 (95% CI: -0.55 to -0.10)] and up to long-term follow-up and a medium magnitude of effect improving function at both immediate post treatment and at short-term follow-up [SMDp -0.45 (95%CI: -0.72 to -0.18)]; 4) cervico-scapulothoracic strengthening/stabilization exercises to improve pain and function at intermediate term [SMDp -14.90 (95% CI:-22.40 to -7.39)]; 5) Mindfulness exercises (Qigong) minimally improved function but not global perceived effect at short term. Low evidence suggests 1) breathing exercises; 2) general fitness training; 3) stretching alone; and 4) feedback exercises combined with pattern synchronization may not change pain or function at immediate post treatment to short-term follow-up. Very low evidence suggests neuromuscular eye-neck co-ordination/proprioceptive exercises may improve pain and function at short-term follow-up.For chronic cervicogenic headache, moderate quality evidence supports static-dynamic cervico-scapulothoracic strengthening/endurance exercises including pressure biofeedback immediate post treatment and probably improves pain, function and global perceived effect at long-term follow-up. Low grade evidence supports sustained natural apophyseal glides (SNAG) exercises.For acute radiculopathy, low quality evidence suggests a small benefit for pain reduction at immediate post treatment with cervical stretch/strengthening/stabilization exercises.
AUTHORS' CONCLUSIONS: No high quality evidence was found, indicating that there is still uncertainty about the effectiveness of exercise for neck pain. Using specific strengthening exercises as a part of routine practice for chronic neck pain, cervicogenic headache and radiculopathy may be beneficial. Research showed the use of strengthening and endurance exercises for the cervico-scapulothoracic and shoulder may be beneficial in reducing pain and improving function. However, when only stretching exercises were used no beneficial effects may be expected. Future research should explore optimal dosage.
颈部疼痛很常见,会导致功能障碍且成本高昂。运动是一种治疗方法。
评估运动对改善颈部疼痛成人的疼痛、功能障碍、功能、患者满意度、生活质量和整体感知效果的有效性。
我们检索了MEDLINE、MANTIS、ClinicalTrials.gov以及其他三个计算机化数据库,检索时间截至2014年1月至5月,此外还检索了其他来源(参考文献核对、引文检索、与作者联系)。
我们纳入了随机对照试验(RCT),比较单一治疗性运动与对照组,研究对象为患有颈部疼痛且伴有或不伴有颈源性头痛或神经根病的成年人。
两位综述作者独立进行试验筛选、数据提取、“偏倚风险”评估和临床相关性分析。使用GRADE评估证据质量。在判断临床和统计异质性后,对相对风险和标准化均值差(SMD)进行荟萃分析,并给出95%置信区间(CI)。
27项试验(分析了2485例/随机分配3005例参与者)符合我们的纳入标准。仅针对急性颈部疼痛,未发现证据。对于慢性颈部疼痛,中等质量证据支持:1)颈肩胸和上肢力量训练可在治疗后立即及短期随访时显著改善中度至大量疼痛[合并标准化均值差(SMDp)-0.71(95%CI:-1.33至-0.10)];(2)肩胸和上肢耐力训练在治疗后立即及短期随访时对疼痛有轻微有益影响;(3)颈部、肩部和肩胸联合强化及伸展运动在治疗后立即对疼痛的有益影响程度从小到大都有[SMDp -0.33(95%CI:-0.55至-0.10)],直至长期随访,且在治疗后立即及短期随访时对改善功能有中等程度影响[SMDp -0.45(95%CI:-0.72至-0.18)];(4)颈肩胸强化/稳定训练可在中期改善疼痛和功能[SMDp -14.90(95%CI:-22.40至-7.39)];(5)正念运动(气功)在短期内对功能有轻微改善,但对整体感知效果无改善。低质量证据表明:1)呼吸运动;2)一般健身训练;3)单纯伸展运动;4)反馈运动与模式同步相结合在治疗后立即至短期随访期间可能不会改变疼痛或功能。极低质量证据表明神经肌肉眼颈协调/本体感觉运动可能在短期随访时改善疼痛和功能。对于慢性颈源性头痛,中等质量证据支持在治疗后立即进行包括压力生物反馈的静态-动态颈肩胸强化/耐力训练,可能在长期随访时改善疼痛、功能和整体感知效果。低质量证据支持持续自然关节突滑动(SNAG)运动。对于急性神经根病,低质量证据表明颈部伸展/强化/稳定训练在治疗后立即对减轻疼痛有轻微益处。
未发现高质量证据,这表明运动对颈部疼痛有效性仍存在不确定性。将特定强化运动作为慢性颈部疼痛、颈源性头痛和神经根病常规治疗的一部分可能有益。研究表明,对颈肩胸和肩部进行强化和耐力训练可能有助于减轻疼痛和改善功能。然而,仅使用伸展运动可能不会产生有益效果。未来研究应探索最佳剂量。