Martínez A, Sánchez M, Roselló R, Seltzer R, Alonso C, de Andrés L
Department of Diagnostic Radiology, Hospital de Sant Pau, Universidad Autonoma, Barcelona, Spain.
Gastrointest Radiol. 1989 Winter;14(1):49-54. doi: 10.1007/BF01889154.
A retrospective analysis was made of 78 patients presenting breast neoplasm with hepatic metastases confirmed by ultrasound. Clinical hepatomegaly was present in 61%. The serum glutamic-oxaloacetic transaminase (SGOT) was elevated in 72%, the serum glutamic-pyruvic transaminase (SGPT) in 56%, the serum alkaline phosphatase (Aph) in 86%, and the gamma-glutamil transpeptidase (GGT) in 76%. A hypoechogenic multiple nodular pattern (HMN) was observed in 69%, a diffuse hypoechogenic pattern (DH) in 15%, and a mixed multiple nodular pattern (MMN) in 11%. No single nodular pattern was presented in any patient. The univariate analysis showed a better survival rate in patients with a mixed pattern (mean 11 months, range 1-29 months) (p = 0.027). No significant differences were observed regarding the remaining patterns, age, presence or not of hepatomegaly, or altered enzymatic values.
对78例经超声证实有肝转移的乳腺肿瘤患者进行了回顾性分析。61%的患者出现临床肝肿大。72%的患者血清谷草转氨酶(SGOT)升高,56%的患者血清谷丙转氨酶(SGPT)升高,86%的患者血清碱性磷酸酶(Aph)升高,76%的患者γ-谷氨酰转肽酶(GGT)升高。69%的患者观察到低回声多发结节型(HMN),15%的患者为弥漫性低回声型(DH),11%的患者为混合多发结节型(MMN)。没有患者表现为单结节型。单因素分析显示,混合型患者的生存率更高(平均11个月,范围1 - 29个月)(p = 0.027)。在其余类型、年龄、是否存在肝肿大或酶值改变方面未观察到显著差异。