a Department of Molecular Biotechnology , School of Life & Environmental Sciences, Konkuk University , Seoul , Korea.
Crit Rev Food Sci Nutr. 2016 Oct 2;56(13):2231-49. doi: 10.1080/10408398.2014.910748.
Glucosinolates are the major bioactive secondary metabolites found in the Brassicaceae family and studied extensively in biosynthetic and application perspectives. Because of their potential applications in the welfare of plants (protection against plant pathogens) and human life (prevention of cancer and other diseases), these compounds attracted much interest in the scientific community. In this review, we presented updates on glucosinolate derivatives in protection against microbial pathogens and endocrine related diseases in human. Further, the mechanism of action of glucosinolate derivatives and the strategies to improve their efficiency through modern approaches were discussed. Finally, the genetic enrichment of their contents in plant systems has also been discussed.
硫代葡萄糖苷是芸薹属植物中主要的生物活性次生代谢产物，在生物合成和应用方面的研究非常广泛。由于其在植物福利（防治植物病原体）和人类生活（预防癌症和其他疾病）方面的潜在应用，这些化合物在科学界引起了广泛关注。在这篇综述中，我们介绍了硫代葡萄糖苷衍生物在防治人类微生物病原体和与内分泌相关疾病方面的最新进展。此外，还讨论了硫代葡萄糖苷衍生物的作用机制以及通过现代方法提高其效率的策略。最后，还讨论了在植物系统中富集其含量的遗传方法。
