Duan Runqing, Shi Hongcheng
Department of Radiology, The First People's Hospital of Xiaoshan, Hangzhou, 311200, Zhejiang Province, China,
Jpn J Radiol. 2015 Mar;33(3):131-9. doi: 10.1007/s11604-015-0390-9. Epub 2015 Jan 29.
To evaluate the practical application of SPECT, CT, and SPECT/CT to the diagnosis of rib diseases, and to compare their accuracies in differentiating benign and malignant rib diseases.
SPECT, CT, and SPECT/CT were applied to 237 patients. 190 cases in total, with 305 focal lesions, agreed to clinical follow-up. Statistically significant differences (p < 0.05) were observed among these imaging modalities when their diagnosis agreement ratios (i.e., the percentage of correct diagnoses achieved using a particular imaging modality) were compared.
For the 81 cases that were confirmed to be malignant, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 55.56, 76.54, and 92.59 %, respectively, which were significantly different (p < 0.05). For the 97 cases that were confirmed to be benign, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 50.52, 83.51, and 92.78 %, respectively. For the benign cases, the diagnosis agreement ratio of SPECT was significantly different (p < 0.05) from those of CT and SPECT/CT, while the diagnosis agreement ratio of CT was not significantly different (p > 0.05) from that of SPECT/CT.
SPECT/CT fusion imaging yielded significantly improved diagnostic accuracy for rib lesions compared with SPECT or CT alone. SPECT/CT provides markedly more detailed information that is useful for rib lesion diagnosis.
评估单光子发射计算机断层扫描（SPECT）、计算机断层扫描（CT）及SPECT/CT在肋骨疾病诊断中的实际应用，并比较它们在鉴别肋骨良性和恶性疾病方面的准确性。
对237例患者应用SPECT、CT及SPECT/CT进行检查。共有190例患者、305个局灶性病变同意接受临床随访。比较这些成像方式的诊断符合率（即使用特定成像方式获得的正确诊断百分比）时，观察到它们之间存在统计学显著差异（p < 0.05）。
在81例确诊为恶性的病例中，SPECT、CT及SPECT/CT的诊断符合率分别为55.56%、76.54%和92.59%，差异有统计学意义（p < 0.05）。在97例确诊为良性的病例中，SPECT、CT及SPECT/CT的诊断符合率分别为50.52%、83.51%和92.78%。对于良性病例，SPECT的诊断符合率与CT及SPECT/CT的诊断符合率差异有统计学意义（p < 0.05），而CT的诊断符合率与SPECT/CT的诊断符合率差异无统计学意义（p > 0.05）。
与单独的SPECT或CT相比，SPECT/CT融合成像对肋骨病变的诊断准确性有显著提高。SPECT/CT提供了明显更详细的信息，有助于肋骨病变的诊断。
