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头颈部结核:6年回顾性研究。

Head and neck tuberculosis: 6-year retrospective study.

作者信息

Chiesa Estomba Carlos Miguel, Betances Reinoso Frank Alberto, Rivera Schmitz Teresa, Ossa Echeverri Carla Cristina, González Cortés María Jesús, Santidrian Hidalgo Carmelo

机构信息

Servicio de ORL, Complejo Hospitalario Universitario de Vigo, Vigo, España.

Servicio de ORL, Complejo Hospitalario Universitario de Vigo, Vigo, España.

出版信息

Acta Otorrinolaringol Esp. 2016 Jan-Feb;67(1):9-14. doi: 10.1016/j.otorri.2014.11.003. Epub 2015 Jan 25.

DOI:10.1016/j.otorri.2014.11.003
PMID:25630666
Abstract

INTRODUCTION

Pulmonary involvement exists in 80% of cases of infection with Mycobacterium tuberculosis; however, in up to 20% of cases there may be extra-pulmonary involvement. In the ENT area, the most common site is cervical lymphadenitis, affecting approximately 95% of cases.

MATERIALS AND METHODS

This was a retrospective study of patients attending an ENT department in a tertiary hospital for head and neck symptoms that were diagnosed with tuberculosis (TB), between December 2007 and December 2013.

RESULTS

The study included 73 patients, 41 (56.2%) males and 32 (43.8%) females (M/F ratio=1.28), with a mean age of 39.4 years (± 26.5 years; Min 1, Max 88). There were 53 (72.6%) cases of cervical lymphadenopathy, 11 (15%) of laryngeal tuberculosis 3 (4.1%) of hypopharyngeal tuberculosis, and six cases in other locations. Of the total, 14 (19.2%) patients were HIV positive and 10 (13.7%) had a history of contact with relatives who had suffered pulmonary tuberculosis. PCR was performed in 51 (69.8%) cases to confirm being positive, of which 47 (92.1%) cases were.

CONCLUSION

The similarity of tuberculosis to diseases of poor prognosis and the difficulty of its diagnosis make considering tuberculosis necessary when exploring patients with ulcerative or granulomatous ENT lesions. Analysing our results, the incidence of TB according to its ENT area location is similar to that reported in the literature. It is important to make special mention of the use of PCR in our study and the benefits that its implementation means for diagnosis.

摘要

引言

80%的结核分枝杆菌感染病例存在肺部受累;然而,高达20%的病例可能有肺外受累。在耳鼻喉科领域,最常见的部位是颈部淋巴结炎,约占病例的95%。

材料与方法

这是一项对2007年12月至2013年12月期间在一家三级医院耳鼻喉科因头颈部症状被诊断为结核病(TB)的患者进行的回顾性研究。

结果

该研究包括73例患者,男性41例(56.2%),女性32例(43.8%)(男/女比例=1.28),平均年龄39.4岁(±26.5岁;最小1岁,最大88岁)。有53例(72.6%)颈部淋巴结病,11例(15%)喉结核,3例(4.1%)下咽结核,其他部位6例。总共14例(19.2%)患者HIV阳性,10例(13.7%)有与患肺结核亲属接触的病史。51例(69.8%)病例进行了PCR检测以确认阳性,其中47例(92.1%)为阳性。

结论

结核病与预后不良疾病的相似性及其诊断困难使得在探究患有溃疡性或肉芽肿性耳鼻喉病变的患者时必须考虑结核病。分析我们的结果,结核病在耳鼻喉科区域的发病率与文献报道相似。特别值得一提的是我们研究中PCR的使用及其实施对诊断的益处。

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