基因组学：CRISPR基因编辑技术开启基因功能。 - Suppr

Genomics: CRISPR engineering turns on genes.

作者信息

Cho Seung Woo, Chang Howard Y

机构信息

Program in Epithelial Biology and the Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.

出版信息

Nature. 2015 Jan 29;517(7536):560-2. doi: 10.1038/517560a.

DOI:10.1038/517560a

PMID:25631441

Abstract

摘要

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Science. 2014 Nov 28;346(6213):1258096. doi: 10.1126/science.1258096.

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Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9.

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.

Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20.

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.

Nat Biotechnol. 2013 Sep;31(9):833-8. doi: 10.1038/nbt.2675. Epub 2013 Aug 1.

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Cell. 2013 Jul 18;154(2):442-51. doi: 10.1016/j.cell.2013.06.044. Epub 2013 Jul 11.

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28.

Long noncoding RNA as modular scaffold of histone modification complexes.

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相似文献

Genomics: CRISPR engineering turns on genes.

Nature. 2015 Jan 29;517(7536):560-2. doi: 10.1038/517560a.

CRISPR gain-of-function screens.

Nat Methods. 2015 Feb;12(2):102-3. doi: 10.1038/nmeth.3274.

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Mol Cell. 2015 May 21;58(4):560-2. doi: 10.1016/j.molcel.2015.05.016.

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Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10.

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Nature. 2015 Dec 3;528(7580):S12-3. doi: 10.1038/528S12a.

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Nature. 2015 Dec 3;528(7580):S14. doi: 10.1038/528S14a.

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Nature. 2015 Dec 3;528(7580):S10-1. doi: 10.1038/528S10a.

The dark side of the human genome.

Nature. 2016 Oct 13;538(7624):275-277. doi: 10.1038/538275a.

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Nat Biotechnol. 2016 Feb;34(2):192-8. doi: 10.1038/nbt.3450. Epub 2016 Jan 11.

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Nat Genet. 2019 Mar;51(3):365. doi: 10.1038/s41588-019-0374-2.

本文引用的文献

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

Cell. 2015 Jan 15;160(1-2):339-50. doi: 10.1016/j.cell.2014.11.052. Epub 2014 Dec 18.

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10.

Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Science. 2014 Nov 28;346(6213):1258096. doi: 10.1126/science.1258096.

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Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9.

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.

Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20.

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.

Nat Biotechnol. 2013 Sep;31(9):833-8. doi: 10.1038/nbt.2675. Epub 2013 Aug 1.

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Cell. 2013 Jul 18;154(2):442-51. doi: 10.1016/j.cell.2013.06.044. Epub 2013 Jul 11.

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28.

Long noncoding RNA as modular scaffold of histone modification complexes.

Science. 2010 Aug 6;329(5992):689-93. doi: 10.1126/science.1192002. Epub 2010 Jul 8.

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.

Genomics: CRISPR engineering turns on genes.

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