Quang Dang Ngoc, Khamko Vong Anatha, Trang Nguyen Thi, Yen Lam Thi Hai, Dien Pham Huu
Nat Prod Commun. 2014 Dec;9(12):1741-2.
Two new phenylbenzofuran-type stilbenoids named stemofurans X and Y (1, 2) were isolated from the roots of Stemona pierrei and S. tuberosa, respectively, together with ten known compounds. These compounds were stemanthrenes B-C (3, 4), (+)-syringaresinol (5), maistemonine (6), isomaistemonine (7) and sesamin (8) from S. pierrei, and stemophenanthrenes A-C (9-11) and isopinosylvin A (12) from S. tuberosa. Stemofurans X-Y (1, 2) showed moderate cytotoxicity against the four cancer cell lines KB (human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma), and Hep-G2 (hepatocellular carcinoma).
从阔叶百部和直立百部的根部分别分离出两种新的苯基苯并呋喃型二苯乙烯类化合物，命名为百部呋喃X和Y（1, 2），同时还分离出10种已知化合物。这些化合物分别是来自阔叶百部的百部萜烯B - C（3, 4）、（+）-丁香树脂醇（5）、百部碱（6）、异百部碱（7）和芝麻素（8），以及来自直立百部的百部菲A - C（9 - 11）和异落叶松脂醇A（12）。百部呋喃X - Y（1, 2）对四种癌细胞系KB（人表皮癌）、MCF7（人乳腺癌）SK - LU - 1（人肺癌）和Hep - G2（肝癌）显示出中等细胞毒性。
