Bahmani Mahmoud, Mirhoseini Mahmoud, Shirzad Hedayatollah, Sedighi Mehrnoosh, Shahinfard Nejmeh, Rafieian-Kopaei Mahmoud
Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Islamic Republic of Iran.
Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Islamic Republic of Iran.
J Evid Based Complementary Altern Med. 2015 Jul;20(3):228-38. doi: 10.1177/2156587214568457. Epub 2015 Jan 28.
Hyperlipidemia is a prevalent disease and a major component of the metabolic syndrome resulting from various factors. This disease increases morbidity and mortality when combined with other prevalent diseases such as diabetes mellitus, hypertension, and cardiovascular diseases. The side effects of the current lipid-lowering drugs have increased the tendency to move toward traditional and alternative treatments. Epidemiological observations indicate that using alternative treatments, consumption of medicinal plants, diet, and consumption of fruits have had satisfactory results on the effects of hyperlipidemia in many societies. It should be noted that in majority of societies, even developed countries, the tendency toward eating lipid-lowering medicinal plants has increased extensively. Using these plants especially when common remedies cannot control the disease is significant. Although consumption of medicinal plants by hyperlipidemic patients may show improvement in disease state, drug interaction and side effects may cause complications in disease control. Therefore, in this review, apart from introducing some of the reliable plants effective in inhibition and decrease of hyperlipidemia, the possibility of their intoxication and drug interaction is also presented.
高脂血症是一种常见疾病，是由多种因素导致的代谢综合征的主要组成部分。当这种疾病与其他常见疾病如糖尿病、高血压和心血管疾病合并时，会增加发病率和死亡率。当前降脂药物的副作用增加了人们转向传统和替代疗法的趋势。流行病学观察表明，在许多社会中，使用替代疗法、食用药用植物、饮食和食用水果对高脂血症的影响取得了令人满意的效果。应该注意的是，在大多数社会，甚至是发达国家，食用降脂药用植物的趋势已经大幅增加。使用这些植物，尤其是在常用药物无法控制疾病时，具有重要意义。尽管高脂血症患者食用药用植物可能会改善病情，但药物相互作用和副作用可能会在疾病控制中引起并发症。因此，在本综述中，除了介绍一些对抑制和降低高脂血症有效的可靠植物外，还介绍了它们中毒和药物相互作用的可能性。
