Subramaniam Saravanan, Ramachandran Subramaniam, Uthrapathi Subasini, Gnamanickam Victor Rajamanickam, Dubey Govinda Prasad
Department of Pharmacology, PSG College of Pharmacy, Coimbatore 641 004, India.
Indian J Exp Biol. 2011 Apr;49(4):282-8.
The three fractions diethyl ether, ethyl acetate and ethanol. of T. arjuna exerted hypolipidemic and antioxidative effects at two different doses levels of 175 and 350 mg/kg body weight in Poloxamer (PX)-407 induced hyperlipidemic albino Wistar rats. The hypolipidemic and antioxidant effects of T. arjuna fractions were noticed as EtOH > diethyl ether > ethyl acetate. The results suggest that ethanolic fraction of T. arjuna possesses the potent properties of being antioxidant and hypolipidemic than other fractions. In turn, it has therapeutic potential for the prevention of coronary arterial disease.
在泊洛沙姆（PX）-407诱导的高脂血症白化Wistar大鼠中，Terminalia arjuna的三种馏分（二乙醚、乙酸乙酯和乙醇）在175和350毫克/千克体重这两种不同剂量水平下发挥了降血脂和抗氧化作用。Terminalia arjuna馏分的降血脂和抗氧化作用表现为乙醇馏分＞二乙醚＞乙酸乙酯。结果表明，Terminalia arjuna的乙醇馏分比其他馏分具有更强的抗氧化和降血脂特性。相应地，它在预防冠状动脉疾病方面具有治疗潜力。
