Correlation between high-sensitivity C reactive protein and local arterial stiffness measured by radio frequency echotracking system in type 2 diabetic patients.
作者信息
Nurizal Azri, Antono Dono, Wijaya Ika Prasetya, Shatri Hamzah
机构信息
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
出版信息
Acta Med Indones. 2014 Oct;46(4):308-13.
AIM
To identify the correlation between hsCRP and arterial stiffness in type-2 diabetic patients.
METHODS
A cross-sectional study was conducted to assess the plasma levels of hsCRP and carotid arterial stiffness in 40 patients with type-2 diabetes mellitus. The common carotid artery stiffness was evaluated using radio frequency echo-tracking system to determine the local carotid pulse wave velocity (carotid-PWV).
RESULTS
Median value of hsCRP in this study was 4.5 (0.2 to 18.9) mg/L and the average value of local carotid stiffness was 8.8±1.7 m/sec. High sensitive CRP showed a strong correlation with carotid-PWV (r=0.503, P=0.001). hsCRP level was independently associated with carotid-PWV after adjustment for age, body mass index, and mean arterial pressure (r=0.450, P=0.005).
CONCLUSION
Hs-CRP has moderate positive correlation with arterial stiffness in patients with type-2 diabets mellitus.
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