Zou Chunpeng, Jiao Yan, Li Xingwang, Zheng Chao, Chen Maohua, Hu Chunhong
Department of Radiology, The First Affiliated Hospital of Soochow UniversitySuzhou 215006, China; Department of Ultrasonic Diagnosis, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325027, China.
Department of Obstetrics and Gynecology Ultrasonic, Wenzhou City Peoples' Hospital Wenzhou 325000, China.
Int J Clin Exp Med. 2015 Oct 15;8(10):17765-72. eCollection 2015.
This study aimed to investigate the correlation between strain and elasticity of the common carotid artery (CCA) by ultrasonography and evaluate its clinical significance in patients with diabetic nephropathy (DN).
A total of 68 DN patients and 54 healthy subjects were randomly recruited from the Ultrasound Department from April 2014 to March 2015. The maximum of circumferential strain (CSmax), maximum of circumferential strain rate (CSRmax), compliance coefficient (CC) and stiffness index (β) of the CCA were determined by ultrasonography in all the patients, and correlation analysis was performed.
The CC, CSmax and CSRmax in DN group were significantly lower than in healthy controls (P<0.05), but β was markedly higher than in control group (P<0.05). There was a significantly positive correlation of CSmax and CSRmax with CC and a negative correlation with β in both control group and DN group.
There is significant correlation between strain and elastic of the CCA. CSmax and CSRmax may be used to reflect the mechanical characteristics of CCA.
本研究旨在通过超声检查探讨颈总动脉（CCA）应变与弹性之间的相关性，并评估其在糖尿病肾病（DN）患者中的临床意义。
2014年4月至2015年3月期间，从超声科随机招募了68例DN患者和54例健康受试者。对所有患者进行超声检查，测定CCA的圆周应变最大值（CSmax）、圆周应变率最大值（CSRmax）、顺应性系数（CC）和硬度指数（β），并进行相关性分析。
DN组的CC、CSmax和CSRmax显著低于健康对照组（P<0.05），但β显著高于对照组（P<0.05）。对照组和DN组中，CSmax和CSRmax与CC均呈显著正相关，与β呈负相关。
CCA的应变与弹性之间存在显著相关性。CSmax和CSRmax可用于反映CCA的力学特性。
