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Industry sponsorship and research outcome.行业赞助与研究成果。
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2
Selective publication of antidepressant trials and its influence on apparent efficacy.抗抑郁药物试验的选择性发表及其对表面疗效的影响。
N Engl J Med. 2008 Jan 17;358(3):252-60. doi: 10.1056/NEJMsa065779.
3
American College of Occupational and Environmental Medicine (ACOEM): a professional association in service to industry.美国职业与环境医学学会(ACOEM):一个服务于行业的专业协会。
Int J Occup Environ Health. 2007 Oct-Dec;13(4):404-26. doi: 10.1179/oeh.2007.13.4.404.
4
Adverse effects of inhaled corticosteroids in funded and nonfunded studies.在有资金支持和无资金支持的研究中吸入性糖皮质激素的不良反应。
Arch Intern Med. 2007 Oct 22;167(19):2047-53. doi: 10.1001/archinte.167.19.2047.
5
Manipulated data in Shell's Benzene Historical Exposure Study.壳牌苯历史暴露研究中的数据操纵行为。
Int J Occup Environ Health. 2007 Apr-Jun;13(2):222-32. doi: 10.1179/oeh.2007.13.2.222.
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Factors associated with findings of published trials of drug-drug comparisons: why some statins appear more efficacious than others.已发表的药物与药物对比试验结果的相关因素:为何某些他汀类药物似乎比其他药物更有效。
PLoS Med. 2007 Jun;4(6):e184. doi: 10.1371/journal.pmed.0040184.
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Industry influence on occupational and environmental public health.行业对职业与环境公共卫生的影响。
Int J Occup Environ Health. 2007 Jan-Mar;13(1):107-17. doi: 10.1179/107735207800244929.
8
Source of funding and results of studies of health effects of mobile phone use: systematic review of experimental studies.手机使用对健康影响的研究资金来源及结果:实验研究的系统评价
Environ Health Perspect. 2007 Jan;115(1):1-4. doi: 10.1289/ehp.9149.
9
Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review.Cochrane系统评价与行业支持的Meta分析及相同药物的其他Meta分析的比较:系统评价
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10
Lifting the veil of secrecy from industry funding of nonprofit health organizations.揭开非营利性健康组织行业资金的神秘面纱。
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一种评估财务利益冲突的新方法。

A new method for scoring financial conflicts of interest.

作者信息

Maharaj S V M

出版信息

Int J Occup Environ Health. 2015;21(1):49-52. doi: 10.1179/2049396714Y.0000000097.

DOI:10.1179/2049396714Y.0000000097
PMID:25633929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4273519/
Abstract

BACKGROUND

There is a large and consistent body of evidence showing that research sponsored by for-profit industries tends to have pro-industry conclusions in comparison with similar research or re-analyses not funded by industry. Disclosure of financial conflicts via statements is presently the standard method for notification of potential biases. However, many journals are not consistent in publishing financial conflicts of interest (FCoI) statements. Furthermore, even when divulged, disclosure merely shifts the burden of evaluating conflicts to readers and the general public. Moreover, there has been an absence of a means of quantifying FCoI.

OBJECTIVES

To propose a solution for the question: What are we doing about FCoI that continue to compromise the integrity of the scientific enterprise?

METHODS

The FCoI Scale was developed for scoring and comparing FCoI and describing potential biases.

RESULTS

The FCoI Scale consists of a score that may be expressed in whole numbers and decimal fractions, correlated to descriptive terms for potential biases and examples of financial conflicts at 11 levels.

CONCLUSIONS

The FCoI score (FCoIS) provides a means for a more uniform and concise method of disclosure compared to statements, while at the same time permitting flexibility. It encourages the disclosure of relevant information and transparency in the reporting of financial conflicts. The FCoI Scale has the potential to become the standard basis for measuring, reporting, and comparing financial conflicts, suitable for disciplines in science, medicine, and beyond.

摘要

背景

大量且一致的证据表明,与非行业资助的类似研究或重新分析相比,营利性行业资助的研究往往得出有利于行业的结论。通过声明披露财务冲突目前是通知潜在偏见的标准方法。然而,许多期刊在发表利益冲突(FCoI)声明方面并不一致。此外,即使披露了,披露也只是将评估冲突的负担转移给读者和公众。而且,一直缺乏量化FCoI的方法。

目的

针对“我们如何应对持续损害科学事业诚信的FCoI问题”提出解决方案。

方法

开发FCoI量表用于对FCoI进行评分和比较,并描述潜在偏见。

结果

FCoI量表由一个可以用整数和小数表示的分数组成,与11个级别的潜在偏见描述术语和财务冲突示例相关。

结论

与声明相比,FCoI分数(FCoIS)提供了一种更统一、简洁的披露方法,同时允许灵活性。它鼓励在财务冲突报告中披露相关信息和保持透明度。FCoI量表有可能成为衡量、报告和比较财务冲突的标准基础,适用于科学、医学及其他学科。