Zielhuis G A, Rach G H, van den Broek P
Department of Epidemiology, University of Nijmegen, The Netherlands.
Lancet. 1989 Feb 11;1(8633):311-4. doi: 10.1016/s0140-6736(89)91317-2.
1439 Dutch children were included in a randomised trial to evaluate the efficacy of preschool screening for otitis media with effusion (OME) by 3-monthly tympanometry. Children with bilateral OME on two consecutive occasions were referred for further investigation and then, if parents gave their consent, allocated at random to treatment or non-treatment groups. The effect of childhood screening for OME and subsequent treatment was evaluated by assessment of language performance; no benefit was found, mainly because of the large degree of spontaneous recovery.
1439名荷兰儿童被纳入一项随机试验，以评估通过每3个月进行一次鼓室声导抗测量来筛查学龄前儿童中耳积液（OME）的疗效。连续两次出现双侧OME的儿童被转介进行进一步检查，然后，如果家长同意，随机分配到治疗组或非治疗组。通过评估语言能力来评估儿童OME筛查及后续治疗的效果；未发现有获益，主要原因是自发恢复程度较高。
