Yang R-F, Liu X-Y, Lin Z, Zhang G
Department of Cardiology, Second Affiliated Hospital of Kunming Medical University, Research Laboratory of Coronary Heart Diseases, Cardiovascular Disease Institute of Yunnan Province, China.
Eur Rev Med Pharmacol Sci. 2015 Jan;19(1):113-8.
Coronary disease is analyzed through common lipid profiles, but these analyses fail to account for residual risk due to abdominal weight and elevated TG levels. We aimed to investigate the relationship between the waist circumference × triglyceride index (WT index) and the Coronary Artery Score (CAS) in patients with coronary heart disease.
346 patients in our Cardiology Department were recruited from September 2007 to August 2011 and divided into two groups according to whether the patients presented with metabolic syndrome. We performed coronary angiography using the standard Judkins method. The severity of coronary artery stenosis and the CAS were calculated and analyzed with a computerized quantitative analysis system. The signs index, which includes the body mass index (BMI), waist circumference, hip circumference, waist-hip-ratio, and waist-height-ratio, the blood glucose and blood lipid index of all the patients were collected and used to calculate the WT index (waist circumference x triglyceride index.
We performed a correlative analysis with age, gender, body mass index, blood glucose and blood lipid, blood pressure and other risk indicators of all patients as the dependent variables and the CAS as the independent variable. We show that the CAS is positively correlated to the WT index. Several lipid profiles and waist circumference were significantly associated with the CAS.
The WT index is correlated to the CAS and is a good predictor for the development of coronary artery disease; it can be applied in the clinic for early intervention in populations at risk for coronary heart disease.
通过常见血脂指标分析冠心病,但这些分析未考虑腹部肥胖和甘油三酯水平升高所致的残余风险。我们旨在研究冠心病患者腰围×甘油三酯指数(WT指数)与冠状动脉积分(CAS)之间的关系。
选取2007年9月至2011年8月在我院心内科就诊的346例患者,根据是否患有代谢综合征分为两组。采用标准Judkins法进行冠状动脉造影。使用计算机定量分析系统计算并分析冠状动脉狭窄程度和CAS。收集所有患者的体征指标,包括体重指数(BMI)、腰围、臀围、腰臀比和腰高比,以及血糖和血脂指标,用于计算WT指数(腰围×甘油三酯指数)。
以所有患者的年龄、性别、体重指数、血糖和血脂、血压等风险指标为因变量,CAS为自变量进行相关性分析。结果显示,CAS与WT指数呈正相关。多项血脂指标和腰围与CAS显著相关。
WT指数与CAS相关,是冠心病发生的良好预测指标;可应用于临床,对冠心病高危人群进行早期干预。