Meo S A, Memon A N, Sheikh S A, Rouq F A, Usmani A Mahmood, Hassan A, Arian S A
Department of Physiology, Pharmacology, University Diabetes Centre; College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Eur Rev Med Pharmacol Sci. 2015 Jan;19(1):123-8.
Air pollution is a novel risk factor for insulin resistance and occurrence of type 2 diabetes mellitus (T2DM), but the evidence is limited and diverse. Therefore, the aim of this study was to assess the effect of environmental air pollution on incidence of type 2 diabetes mellitus.
In this study, we identified 102 published studies through a systematic data base search including ISI-Web of Science, EMBASE and PubMed. We searched the related literature by using the key terms including diabetes mellitus, air pollution, occupational and environmental pollution, gaseous, NO2, particulate matter pollutants PM2.5, and PM10. Studies in which diabetes mellitus, insulin resistance, air pollution, occupational and environmental pollution was discussed were included in the study. No confines on publication status, study design or language of publication were considered. Descriptive and quantitative information were extracted from the selected literature. Finally we included 21 publications and remaining studies were excluded.
Air pollution is a leading cause of insulin resistance and incidence of type 2 diabetes mellitus. The association between air pollution and diabetes is stronger for traffic associated pollutants, gaseous, nitrogen dioxide, tobacco smoke and particulate matter.
Exposure to air pollutants is significantly associated with increased risk of type 2 diabetes mellitus. It is suggested that, environmental protection officials must take high priority steps to minimize the air pollution, hence to decrease the incidence of type 2 diabetes mellitus.
空气污染是胰岛素抵抗和2型糖尿病（T2DM）发生的一个新的危险因素，但证据有限且多样。因此，本研究的目的是评估环境空气污染对2型糖尿病发病率的影响。
在本研究中，我们通过系统的数据库检索，包括ISI-Web of Science、EMBASE和PubMed，确定了102项已发表的研究。我们使用包括糖尿病、空气污染、职业和环境污染、气体、二氧化氮、颗粒物污染物PM2.5和PM10等关键词来检索相关文献。纳入讨论糖尿病、胰岛素抵抗、空气污染、职业和环境污染的研究。不考虑发表状态、研究设计或发表语言的限制。从选定的文献中提取描述性和定量信息。最后我们纳入了21篇出版物，其余研究被排除。
空气污染是胰岛素抵抗和2型糖尿病发病率的主要原因。与交通相关污染物、气体、二氧化氮、烟草烟雾和颗粒物之间，空气污染与糖尿病的关联更强。
暴露于空气污染物与2型糖尿病风险增加显著相关。建议环境保护官员必须高度优先采取措施，尽量减少空气污染，从而降低2型糖尿病的发病率。
