Thomas Ronald L, Zidan Marwan A, Slovis Thomas L
Department of Pediatrics, Children's Research Center of Michigan, Pediatric Prevention Research Unit, Wayne State University School of Medicine, 3901 Beaubien Blvd., Detroit, MI, 48201, USA,
Pediatr Radiol. 2015 Feb;45(2):146-52. doi: 10.1007/s00247-014-2882-7. Epub 2015 Jan 31.
The intent of this manuscript is to provide guidance and support to clinicians and investigators for reporting the results of screening and diagnostic tests. This article is the first of two parts addressing statistics in imaging research. In this part validity measures are discussed. In part II reliability measures will be discussed. In discussing validity, the following concepts will be introduced: (1) functions of diagnostic tests, (2) statistical characteristics of diagnostic tests and application of validity measures, (3) power and sample size for testing the sensitivity and specificity of the diagnostic test, (4) statistical versus clinical significance and (5) characteristics of a useful diagnostic test.
本手稿旨在为临床医生和研究人员报告筛查和诊断测试结果提供指导与支持。本文是关于影像研究统计学的两部分系列文章中的第一篇。在这一部分中，将讨论有效性测量。在第二部分中将讨论可靠性测量。在讨论有效性时，将引入以下概念：（1）诊断测试的功能；（2）诊断测试的统计特征及有效性测量的应用；（3）测试诊断测试敏感性和特异性的效能与样本量；（4）统计学意义与临床意义；以及（5）有用诊断测试的特征。
