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日间小睡和夜间睡眠时间与新发糖尿病的关系:一项中国老年人群的队列研究。

Daytime Napping and Nighttime Sleep Duration with Incident Diabetes Mellitus: A Cohort Study in Chinese Older Adults.

机构信息

Department of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China.

出版信息

Int J Environ Res Public Health. 2021 May 9;18(9):5012. doi: 10.3390/ijerph18095012.

Abstract

BACKGROUND

We aimed to examine the longitudinal associations between daytime napping and nighttime sleep duration with the risk of diabetes mellitus (DM) among Chinese elderly using data from the China Health and Retirement Longitudinal Study (CHARLS).

METHODS

A cohort study was conducted among 2620 participants aged 60 years or above. Information on daytime napping and nighttime sleep duration was self-reported during the 2011 baseline survey. DM status during the 2015 follow-up survey was confirmed according to the American Diabetes Association criteria.

RESULTS

Individuals with long daytime napping (>1 h/day) had increased risk of developing DM than non-nappers (adjusted RR = 1.52, 95%CI: 1.10, 2.10). In addition, we observed a U-shaped association between nighttime sleep duration and incident DM risk. We further found that nappers with <4 h of nighttime sleep, and those with >1 h of daytime napping and >6 h nighttime sleep had approximately two-fold elevated risk of DM, compared to non-nappers with 6-8 h of nighttime sleep.

CONCLUSION

Long daytime napping and extreme nighttime sleep duration were associated with increased DM risk among Chinese elderly. There was a joint effect of long daytime napping and nighttime sleep duration on the risk of DM.

摘要

背景

本研究旨在利用中国健康与养老追踪调查(CHARLS)的数据,探讨中国老年人日间小睡和夜间睡眠时间与糖尿病风险之间的纵向关联。

方法

本研究为队列研究,共纳入 2620 名 60 岁及以上的参与者。在 2011 年基线调查期间,通过自我报告的方式收集日间小睡和夜间睡眠时间信息。在 2015 年随访调查中,根据美国糖尿病协会的标准确定糖尿病状态。

结果

与不午睡者相比,长时间午睡(>1 小时/天)者发生糖尿病的风险更高(调整后的 RR = 1.52,95%CI:1.10,2.10)。此外,我们还观察到夜间睡眠时间与新发糖尿病风险之间呈 U 型关联。进一步发现,与夜间睡眠时间为 6-8 小时的非午睡者相比,夜间睡眠时间<4 小时、日间小睡>1 小时且夜间睡眠时间>6 小时的午睡者发生糖尿病的风险约增加两倍。

结论

中国老年人中,长时间日间小睡和极端夜间睡眠时间与糖尿病风险增加有关。日间小睡时间和夜间睡眠时间对糖尿病风险存在联合作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4011/8125963/988eb008c40a/ijerph-18-05012-g001.jpg

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