基本促分泌素是如何激活肥大细胞的？ - Suppr

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超能文献

How do basic secretagogues activate mast cells?

作者信息

Seifert Roland

机构信息

Hannover Medical School, Institute of Pharmacology, Carl-Neuberg-Straße 1, 30625, Hannover, Germany,

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 2015 Mar;388(3):279-81. doi: 10.1007/s00210-015-1093-6. Epub 2015 Feb 1.

DOI:10.1007/s00210-015-1093-6

PMID:25637583

Abstract

摘要

相似文献

How do basic secretagogues activate mast cells?基本促分泌素是如何激活肥大细胞的？

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Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions.鉴定对伪过敏性药物反应至关重要的肥大细胞特异性受体。

Nature. 2015 Mar 12;519(7542):237-41. doi: 10.1038/nature14022. Epub 2014 Dec 17.

G protein-dependent activation of mast cell by peptides and basic secretagogues.肽类和碱性促分泌剂通过G蛋白依赖性途径激活肥大细胞。

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Mast cell-MrgprB2: sensing secretagogues or a means to overreact?肥大细胞-MrgprB2：感知促分泌剂还是过度反应的一种方式？

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C3a receptors signaling in mast cells.肥大细胞中的C3a受体信号传导

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Targeting human mast cells expressing g-protein-coupled receptors in allergic diseases.针对变应性疾病中表达G蛋白偶联受体的人肥大细胞。

Allergol Int. 2008 Sep;57(3):197-203. doi: 10.2332/allergolint.R-08-163.

Helicobacter pylori neutrophil-activating protein induces release of histamine and interleukin-6 through G protein-mediated MAPKs and PI3K/Akt pathways in HMC-1 cells.幽门螺杆菌中性粒细胞激活蛋白通过G蛋白介导的丝裂原活化蛋白激酶和磷脂酰肌醇-3激酶/蛋白激酶B途径诱导HMC-1细胞释放组胺和白细胞介素-6。

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Activation of mast cells by trimeric G protein Gi3; coupling to the A3 adenosine receptor directly and upon T cell contact.三聚体 G 蛋白 Gi3 激活肥大细胞；通过 T 细胞接触直接与 A3 腺苷受体偶联。

J Immunol. 2010 Apr 1;184(7):3677-88. doi: 10.4049/jimmunol.0901333. Epub 2010 Feb 26.

Autoantibodies against G-protein-coupled receptors modulate heart mast cells.

Cell Mol Immunol. 2007 Apr;4(2):127-33.

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本文引用的文献

Early treatment of food-induced anaphylaxis with epinephrine is associated with a lower risk of hospitalization.用肾上腺素对食物诱发的过敏反应进行早期治疗，可降低住院风险。

J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):57-62. doi: 10.1016/j.jaip.2014.07.004. Epub 2014 Sep 8.

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions.鉴定对伪过敏性药物反应至关重要的肥大细胞特异性受体。

Nature. 2015 Mar 12;519(7542):237-41. doi: 10.1038/nature14022. Epub 2014 Dec 17.

Mast cells in human health and disease.人体健康与疾病中的肥大细胞。

Methods Mol Biol. 2015;1220:93-119. doi: 10.1007/978-1-4939-1568-2_7.

Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.马蜂毒肽通过内源性线粒体途径诱导B16F10-Nex2黑色素瘤细胞凋亡，并在体内显示出抗肿瘤活性。

Peptides. 2015 Jun;68:113-9. doi: 10.1016/j.peptides.2014.09.024. Epub 2014 Oct 14.

Distinct signalling pathways of murine histamine H1- and H4-receptors expressed at comparable levels in HEK293 cells.在HEK293细胞中以相当水平表达的小鼠组胺H1和H4受体的不同信号通路。

PLoS One. 2014 Sep 22;9(9):e107481. doi: 10.1371/journal.pone.0107481. eCollection 2014.

Molecular and cellular analysis of human histamine receptor subtypes.人类组胺受体亚型的分子和细胞分析。

Trends Pharmacol Sci. 2013 Jan;34(1):33-58. doi: 10.1016/j.tips.2012.11.001. Epub 2012 Dec 17.

Agents that induce pseudo-allergic reaction.诱发假性过敏反应的药物。

Drug Discov Ther. 2011 Oct;5(5):211-9. doi: 10.5582/ddt.2011.v5.5.211.

Activation and inhibition of G proteins by lipoamines.

Mol Pharmacol. 2002 Mar;61(3):628-36. doi: 10.1124/mol.61.3.628.

G protein antagonists.

Trends Pharmacol Sci. 1999 Jun;20(6):237-45. doi: 10.1016/s0165-6147(99)01337-1.

Alpha helix content of G protein alpha subunit is decreased upon activation by receptor mimetics.G蛋白α亚基的α螺旋含量在被受体模拟物激活后会降低。

J Biol Chem. 1998 Feb 6;273(6):3247-52. doi: 10.1074/jbc.273.6.3247.

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