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机器人甲状旁腺切除术是否是治疗原发性甲状旁腺功能亢进的靶向开放甲状旁腺切除术的可行且安全的替代方法?

Is robotic parathyroidectomy a feasible and safe alternative to targeted open parathyroidectomy for the treatment of primary hyperparathyroidism?

机构信息

Department of Biosurgery and Surgical Technology, Imperial College London, St. Mary's Hospital, London W2 1NY, United Kingdom.

Department of Otorhinolaryngology and Head & Neck Surgery, Stanford School of Medicine, Stanford, CA, USA.

出版信息

Int J Surg. 2015 Mar;15:55-60. doi: 10.1016/j.ijsu.2015.01.019. Epub 2015 Jan 29.

DOI:10.1016/j.ijsu.2015.01.019
PMID:25638734
Abstract

A best evidence topic was written according to a structured protocol. The question addressed was whether robotic parathyroidectomy (RP) is a feasible and safe alternative to targeted open parathyroidectomy for the treatment of primary hyperparathyroidism (pHPT). A total of 36 papers were identified using the reported searches of which 5 represented the best evidence to answer the clinical question. The authors, date, journal, study type, population, main outcome measures and results are tabulated. Targeted parathyroidectomy constitutes the co-gold-standard procedure for pHPT with results equivalent to bilateral cervical exploration. This has led to the proliferation of minimally invasive parathyroidectomy (MIP) techniques for pre-operatively localised adenomas. None has been shown to be overwhelmingly superior. RP constitutes the most recent addition. RP overcomes the limitations of conventional endoscopic surgery and simultaneously avoids a neck scar by concealing it in the axilla or infraclavicular area. The evidence from the present review shows that RP is feasible and leads to a superior cosmetic result compared to targeted open parathyroidectomy (TOP) with an equivalent safety profile. As with every surgical technique, appropriate patient selection is crucial. Long-term data are currently awaited on RP especially in view of its high cost and long operative time compared to TOP and other MIP techniques. Hence, RP offers a viable but costly alternative to other forms of MIP in patients where even the smallest and most cosmetic neck scar is not an option.

摘要

一个最佳证据主题是根据结构化方案编写的。提出的问题是,机器人甲状旁腺切除术(RP)是否是治疗原发性甲状旁腺功能亢进症(pHPT)的靶向开放性甲状旁腺切除术的可行且安全的替代方法。使用报告的搜索共确定了 36 篇论文,其中 5 篇代表了回答临床问题的最佳证据。作者、日期、期刊、研究类型、人群、主要观察指标和结果均列于表中。靶向甲状旁腺切除术是 pHPT 的联合金标准手术,其结果与双侧颈部探查相当。这导致了微创甲状旁腺切除术(MIP)技术在术前定位腺瘤的广泛应用。但没有一种技术被证明具有压倒性优势。RP 是最新的一种技术。RP 克服了传统内镜手术的局限性,同时通过将其隐藏在腋窝或锁骨下区域来避免颈部疤痕。本综述的证据表明,与靶向开放性甲状旁腺切除术(TOP)相比,RP 具有可行性,并具有更好的美容效果,且安全性相当。与每种手术技术一样,适当的患者选择至关重要。目前正在等待关于 RP 的长期数据,特别是考虑到与 TOP 和其他 MIP 技术相比,它的成本高且手术时间长。因此,对于那些即使最小和最美容的颈部疤痕也不是选择的患者,RP 提供了一种可行但昂贵的替代其他形式的 MIP 的选择。

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