儿童流感病毒感染相关的塑料支气管炎：14例报告
Plastic bronchitis associated with influenza virus infection in children: a report on 14 cases.
作者信息
Zhang Jianhui, Kang Xiaolei
机构信息
Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
出版信息
Int J Pediatr Otorhinolaryngol. 2015 Apr;79(4):481-6. doi: 10.1016/j.ijporl.2015.01.002. Epub 2015 Jan 15.
BACKGROUND
Plastic bronchitis (PB) is a rare disease characterized by formation of bronchial casts. It is usually associated with congenital heart disease, sickle cell disease, lymphoma, and lung diseases such as asthma and pneumonia.
OBJECTIVES
To report 14 cases of PB with influenza A or influenza B infection.
METHODS
We analyzed the clinical manifestations, bronchoscopic and histologic findings, clinical courses, and outcomes.
RESULTS
These cases indicate that PB is a life-threatening complication of severe influenza. Plastic bronchitis should be considered in the diagnosis of children with acute respiratory distress such as lung atelectasis accompanied by influenza.
CONCLUSIONS
Diagnosis should be made by bronchial endoscopy and histopathology, and bronchial casts removed as early as possible.
背景
塑料支气管炎（PB）是一种罕见疾病，其特征为支气管铸型形成。它通常与先天性心脏病、镰状细胞病、淋巴瘤以及哮喘和肺炎等肺部疾病相关。
目的
报告14例甲型或乙型流感感染合并塑料支气管炎的病例。
方法
我们分析了临床表现、支气管镜检查和组织学检查结果、临床病程及转归。
结果
这些病例表明，塑料支气管炎是重症流感的一种危及生命的并发症。在诊断伴有流感的急性呼吸窘迫患儿（如肺不张）时应考虑塑料支气管炎。
结论
应通过支气管内镜检查和组织病理学进行诊断，并尽早清除支气管铸型。
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