Kilgenstein Helen J, Schöniger Sandra, Schoon Doris, Schoon Heinz-Adolf
Institute of Veterinary-Pathology, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 33, 04103 Leipzig, Germany.
Institute of Veterinary-Pathology, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 33, 04103 Leipzig, Germany.
Res Vet Sci. 2015 Apr;99:171-9. doi: 10.1016/j.rvsc.2015.01.005. Epub 2015 Jan 15.
After their retirement from sports, performance mares often show a poor breeding success. The objective of this study was the microscopic evaluation of endometrial biopsies of retired sports mares (n = 189) to search for alterations that may explain subfertility. Mares of this study aged 3-23 years showed endometritis (30%) and endometrosis (77%); mild forms predominated. In regard to those mares biopsied during the breeding season (n = 99), 50% had glandular differentiation disorders, i.e. glandular inactivity (8%) or irregular glandular differentiation (42%). Compared to literature data retrieved from mainly non-performance mares, the sports mares of this study showed a similar prevalence of endometrosis and endometritis, but a much higher prevalence of glandular differentiation disorders. The most common cause of the latter is an ovarian dysfunction. Results of this study indicate an association between glandular maldifferentiation of the endometrium and the clinically observed reduced fertility of retired sports mares.
退役后的运动母马往往繁殖成功率较低。本研究的目的是对退役运动母马（n = 189）的子宫内膜活检进行显微镜评估，以寻找可能解释生育力低下的改变。本研究中3至23岁的母马表现出子宫内膜炎（30%）和子宫内膜症（77%）；以轻度形式为主。在繁殖季节接受活检的母马（n = 99）中，50%有腺体分化障碍，即腺体无活性（8%）或不规则腺体分化（42%）。与主要从非运动母马获得的文献数据相比，本研究中的运动母马子宫内膜症和子宫内膜炎的患病率相似，但腺体分化障碍的患病率要高得多。后者最常见的原因是卵巢功能障碍。本研究结果表明，子宫内膜腺体分化异常与临床上观察到的退役运动母马生育力降低之间存在关联。
