谷氨酰胺合成酶在人肝脏中的免疫组织化学定位
Immunohistochemical localization of glutamine synthetase in human liver.
作者信息
Gebhardt R, Schmid H, Fitzke H
机构信息
Physiologisch-chemisches Institut, Tübingen, Federal Republic of Germany.
出版信息
Experientia. 1989 Feb 15;45(2):137-9. doi: 10.1007/BF01954848.
PMID:2563977
Abstract
Glutamine synthetase (GS) of human liver was recognized with a polyclonal antibody to pig brain GS, but failed to stain with an antibody against rat liver GS. Using the latter antibody GS of human liver was shown to be localized within small rings of 1 to 3 hepatocytes surrounding the terminal hepatic venules. This pattern was analogous to that seen in rat and mouse liver.
摘要
用人脑谷氨酰胺合成酶（GS）的多克隆抗体可识别出人类肝脏中的谷氨酰胺合成酶，但用抗大鼠肝脏GS的抗体进行染色时却未成功。使用后一种抗体显示，人类肝脏中的GS定位于围绕终末肝静脉的1至3个肝细胞的小环内。这种模式与在大鼠和小鼠肝脏中观察到的模式类似。
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