Birati Edo Y, Rame J Eduardo
Division of Cardiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Curr Treat Options Cardiovasc Med. 2015 Feb;17(2):361. doi: 10.1007/s11936-014-0361-y.
Ventricular assist device (VAD) thrombosis is one of the most devastating complications for patients on mechanical assist devices, and has been occurring more frequently during the last 3 years for unknown reasons. The diagnosis of VAD thrombosis is challenging and requires knowledge of the various clinical presentations and high vigilance. The current review summarizes various aspects of VAD thrombosis, including possible mechanisms for the formation of VAD thrombus and its clinical presentation, and presents a suggested algorithm in diagnosing this entity, with therapeutic options. High awareness and knowledge of the variable clinical presentations of VAD thrombosis are essential in order to allow early diagnosis, which may decrease the morbidity and mortality associated with this complication.
心室辅助装置（VAD）血栓形成是接受机械辅助装置治疗的患者最严重的并发症之一，在过去3年中其发生率莫名地越来越高。VAD血栓形成的诊断具有挑战性，需要了解各种临床表现并保持高度警惕。本综述总结了VAD血栓形成的各个方面，包括VAD血栓形成的可能机制及其临床表现，并提出了诊断该病症的建议流程以及治疗选择。高度认识和了解VAD血栓形成的各种临床表现对于实现早期诊断至关重要，早期诊断可能会降低与此并发症相关的发病率和死亡率。
