Department of Dermatology & Venereology, Gadjah Mada University, Yogyakarta, Indonesia.
Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
J Eur Acad Dermatol Venereol. 2015 Aug;29(8):1582-9. doi: 10.1111/jdv.12951. Epub 2015 Jan 30.
Shoe dermatitis is a form of contact dermatitis resulting from exposure to shoes. Allergens and types of shoes responsible may vary depending on manufacturing techniques, climatic conditions and indigenous traditions. This study focuses primarily on as yet unexplored shoe dermatitis cases in Indonesia.
To determine the prevalence of shoe dermatitis in the Dermatology outpatient clinic, Sardjito University Hospital, Yogyakarta, Indonesia over a period of 3 years and to identify the responsible allergens.
All patients meeting screening criteria for possible shoe contact dermatitis were patch tested with the European baseline series, shoe series and additional series based on earlier studies of Indonesian leather and shoe manufacturers; some were also patch tested with their own shoe materials and shoe extracts.
Sixty-four (7.1%) of 903 patients with foot skin disorders were diagnosed with shoe dermatitis. Twenty-five (52.1%) of 48 patch-tested patients showed positive reactions to one or more allergens related to footwear. Sixteen patients were patch tested with their own shoe materials; 11 showed positive reactions. The most frequent relevant sensitizers were rubber allergens followed by preservatives, shoe adhesives and leather materials.
Shoe dermatitis is common in Indonesia. Using three series of patch tests, we identified responsible allergens and patterns of sensitization in Indonesian shoe dermatitis patients.
鞋接触性皮炎是一种由鞋暴露引起的接触性皮炎。过敏原和鞋的类型可能因制造技术、气候条件和本土传统而异。本研究主要关注印度尼西亚尚未探索的鞋接触性皮炎病例。
确定在印度尼西亚日惹萨迪约托大学医院皮肤科门诊中鞋接触性皮炎的流行情况，并确定致病过敏原。
对符合可能鞋接触性皮炎筛查标准的所有患者进行斑贴试验，使用欧洲基础系列、鞋系列和基于先前对印度尼西亚皮革和鞋制造商研究的其他系列；一些患者还使用自己的鞋材料和鞋提取物进行斑贴试验。
903 例足部皮肤病患者中，64 例（7.1%）诊断为鞋接触性皮炎。48 例斑贴试验患者中有 25 例（52.1%）对一种或多种与鞋有关的过敏原呈阳性反应。16 例患者用自己的鞋材料进行斑贴试验；11 例呈阳性反应。最常见的相关致敏剂是橡胶过敏原，其次是防腐剂、鞋用粘合剂和皮革材料。
鞋接触性皮炎在印度尼西亚很常见。通过使用三系列斑贴试验，我们确定了印度尼西亚鞋接触性皮炎患者的致病过敏原和致敏模式。
