Wilm Anna, Berneburg Mark
Department of Dermatology, University of Regensburg, Germany.
J Dtsch Dermatol Ges. 2015 Jan;13(1):7-12; quiz 13. doi: 10.1111/ddg.12535.
Many--topically applied or systemically administered--substances may trigger photoallergic skin reactions following exposure to ultraviolet (UV) radiation. While most cases represent photoallergic contact dermatitis due to topically applied agents, systemically triggered photoallergy is considerably less common. The photopatch test--a UV-exposed variant of the conventional patch test--is the mainstay in the diagnosis of photoallergic or phototoxic reactions.
许多物质,无论是局部应用还是全身给药,在暴露于紫外线(UV)辐射后都可能引发光过敏性皮肤反应。虽然大多数病例是由局部应用药物引起的光过敏性接触性皮炎,但全身引发的光过敏则相当少见。光斑贴试验——传统斑贴试验的紫外线暴露变体——是诊断光过敏或光毒性反应的主要方法。