McGwin Gerald, Huisingh Carrie, Jain Shelly G, Girkin Christopher A, Owsley Cynthia
*Department of Epidemiology, School of Public Health Departments of †Ophthalmology ‡Surgery, School of Medicine §Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL ∥Department of Ophthalmology & Visual Science, Ohio State University, Columbus, OH.
J Glaucoma. 2015 Feb;24(2):138-43. doi: 10.1097/IJG.0b013e3182a0761c.
To evaluate the association between the binocular visual field defects in drivers with glaucoma and the risk of motor vehicle collision (MVC) involvement.
A retrospective cohort study was conducted on 438 drivers with glaucoma aged 55 years or older using data from 1994 through 2000. Demographic, clinical, and driving characteristics were obtained from chart abstractions and patient survey. Binocular field measures were generated by combining data from the monocular (central 24-degree radius) fields whereby the binocular field measure was defined as the more sensitive point at each monocular field location. Measures included threshold (TH), total deviation (TD), and pattern deviation (PD); severe impairment in these measures was defined as falling into the worst quartile. MVC data were obtained from police records. Rate ratios (RR) and 95% confidence intervals (CI) were calculated.
Drivers with severely impaired PD measures were twice as likely to have an at-fault MVC compared with those not severely impaired (RR, 2.13; 95% CI, 1.21-3.75); those with severely impaired TH (RR, 1.49; 95% CI, 0.81-2.74) and TD (RR, 1.50; 95% CI, 0.82-2.74) also had an increased rate of at-fault MVCs, although these were not significant. When the binocular central visual field was stratified into 9 regions, drivers with impaired TH, TD, or PD had similarly elevated MVC rates in all regions compared with those not severely impaired, though not all reached statistical significance.
On the basis of clinical measures of visual field routinely used in the management of glaucoma, drivers with glaucoma with severe PD field defects in the binocular field have a higher rate of at-fault MVC compared with those with less impaired or unimpaired binocular visual fields.
评估青光眼患者双眼视野缺损与机动车碰撞(MVC)风险之间的关联。
利用1994年至2000年的数据,对438名年龄在55岁及以上的青光眼患者进行了一项回顾性队列研究。从病历摘要和患者调查中获取人口统计学、临床和驾驶特征。通过合并单眼(中心24度半径)视野数据生成双眼视野测量值,其中双眼视野测量值被定义为每个单眼视野位置上更敏感的点。测量指标包括阈值(TH)、总偏差(TD)和模式偏差(PD);这些指标的严重受损定义为处于最差四分位数。MVC数据来自警方记录。计算率比(RR)和95%置信区间(CI)。
与未严重受损的患者相比,PD测量严重受损的驾驶员发生有过错MVC的可能性是其两倍(RR,2.13;95%CI,1.21 - 3.75);TH(RR,1.49;95%CI,0.81 - 2.74)和TD(RR,1.50;95%CI,0.82 - 2.74)严重受损的驾驶员发生有过错MVC的比率也有所增加,尽管这些差异不显著。当将双眼中心视野分为9个区域时,与未严重受损的驾驶员相比,TH、TD或PD受损的驾驶员在所有区域的MVC发生率同样升高,尽管并非所有差异都具有统计学意义。
根据青光眼治疗中常规使用的视野临床测量指标,与双眼视野受损较轻或未受损的青光眼患者相比,双眼视野中PD视野严重缺损的青光眼患者发生有过错MVC的比率更高。