Gould Felicia, McGuire Laura Stone, Durand Dante, Sabbag Samir, Larrauri Carlos, Patterson Thomas L, Twamley Elizabeth W, Harvey Philip D
Department of Psychiatry, University of Miami Miller School of Medicine.
Department of Psychiatry, University of California, San Diego.
Neuropsychology. 2015 Sep;29(5):675-82. doi: 10.1037/neu0000175. Epub 2015 Feb 2.
Self-assessment deficits, often referred to as impaired insight or unawareness of illness, are well established in people with schizophrenia. There are multiple levels of awareness, including awareness of symptoms, functional deficits, cognitive impairments, and the ability to monitor cognitive and functional performance in an ongoing manner. The present study aimed to evaluate the comparative predictive value of each aspect of awareness on the levels of everyday functioning in people with schizophrenia.
We examined multiple aspects of self-assessment of functioning in 214 people with schizophrenia. We also collected information on everyday functioning rated by high contact clinicians and examined the importance of self-assessment for the prediction of real-world functional outcomes. The relative impact of performance-based measures of cognition, functional capacity, and metacognitive performance on everyday functioning was also examined.
Misestimation of ability emerged as the strongest predictor of real-world functioning and exceeded the influences of cognitive performance, functional capacity performance, and performance-based assessment of metacognitive monitoring. The relative contribution of the factors other than self-assessment varied according to which domain of everyday functioning was being examined, but, in all cases, accounted for less predictive variance.
These results underscore the functional impact of misestimating one's current functioning and relative level of ability. These findings are consistent with the use of insight-focused treatments and compensatory strategies designed to increase self-awareness in multiple functional domains.
自我评估缺陷,通常被称为洞察力受损或对疾病无意识,在精神分裂症患者中已得到充分证实。存在多个意识层面,包括对症状、功能缺陷、认知障碍以及持续监测认知和功能表现能力的意识。本研究旨在评估意识的各个方面对精神分裂症患者日常功能水平的比较预测价值。
我们对214名精神分裂症患者的功能自我评估的多个方面进行了检查。我们还收集了与患者有高接触频率的临床医生对其日常功能的评分信息,并考察了自我评估对预测现实世界功能结局的重要性。我们还研究了基于表现的认知、功能能力和元认知表现测量对日常功能的相对影响。
能力误判成为现实世界功能的最强预测因素,超过了认知表现、功能能力表现以及基于表现的元认知监测评估的影响。除自我评估外,其他因素的相对贡献因所考察的日常功能领域而异,但在所有情况下,其预测方差占比均较小。
这些结果强调了误判自身当前功能和相对能力水平的功能影响。这些发现与使用以洞察力为重点的治疗方法以及旨在提高多个功能领域自我意识的补偿策略相一致。