Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, 1120NW14th Street, Miami, FL 33136, USA.
Schizophr Res. 2011 Sep;131(1-3):250-5. doi: 10.1016/j.schres.2011.05.003. Epub 2011 May 26.
Self reports of everyday functioning on the part of people with schizophrenia have been found to be poorly correlated with the reports of other informants and with their own performance of tests of cognition and functional abilities. However, it is not clear which informants are best for providing accurate reports of everyday functioning. This study examined the convergence between self-reports on the part of people with schizophrenia (n=193), whose real-world functioning was rated by a friend or relative (n=154), or a high contact clinician (n=39) across 6 functional status rating scales. In addition, correlations between these reports and patient's performance on neuropsychological tests and a performance-based measure of functional capacity were also calculated. For convergence between raters, friend or relative informants and patient reports were significantly correlated for 4/6 rating scales. For the smaller sample of clinician informants, the correlations were significant on 2/6 scales. In the analyses of convergence between patient performance scores and functioning ratings, only 1/12 correlations between patient report and performance were significant, while friend or relative reports also were only correlated with performance on one rating scale. In contrast, clinician reports of functioning were correlated with patients' functional capacity performance on 4/6 rating scales and with neuropsychological test performance on 2/6. High contact clinicians appear to generate ratings of everyday functioning that are more closely linked to patients' ability scores than friend or relative informants. Later analyses will determine if there are differences between friend or relative informants.
自我报告的日常功能的精神分裂症患者发现与其他知情人的报告和自己的认知和功能能力测试表现相关性较差。然而,目前尚不清楚哪些知情人最适合提供日常功能的准确报告。本研究考察了精神分裂症患者(n=193)自我报告(n=154)、朋友或亲属(n=39)之间的一致性,6 项功能状态评定量表对其现实生活中的功能进行了评定。此外,还计算了这些报告与患者神经心理学测试和基于表现的功能能力测量的相关性。对于评定者之间的一致性,朋友或亲属知情人和患者报告在 4/6 项评分量表上显著相关。对于较小的临床医生知情人样本,在 2/6 个量表上的相关性显著。在患者表现评分与功能评定之间的一致性分析中,只有 1/12 项患者报告与表现的相关性显著,而朋友或亲属的报告也仅与一个评分量表上的表现相关。相比之下,临床医生对功能的评定与患者在 4/6 项评分量表上的功能能力表现以及在 2/6 项神经心理学测试表现相关。高接触临床医生似乎产生了与患者能力评分更密切相关的日常功能评定,而不是朋友或亲属知情人。后续分析将确定朋友或亲属知情人之间是否存在差异。