通过钯催化的多米诺C-N偶联/氢胺化/C-H芳基化反应合成吲哚并[1,2-f]菲啶
Synthesis of indolo[1,2-f]phenanthridines by Pd-catalyzed domino C-N coupling/hydroamination/C-H arylation reactions.
作者信息
Ngo Thang Ngoc, Ehlers Peter, Dang Tuan Thanh, Villinger Alexander, Langer Peter
机构信息
Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.
出版信息
Org Biomol Chem. 2015 Mar 21;13(11):3321-30. doi: 10.1039/c5ob00013k.
PMID:25644637
Abstract
A new and convenient method for the synthesis of indolo[1,2-f]phenanthridines via palladium-catalyzed domino C-N coupling/hydroamination/C-H arylation reactions was developed. The reactions allow for the synthesis of various phenanthridines in good yields from easily accessible starting materials using a single palladium catalyst.
摘要
开发了一种通过钯催化的多米诺C-N偶联/氢胺化/C-H芳基化反应合成吲哚并[1,2-f]菲啶的新颖便捷方法。该反应使用单一钯催化剂，能够以良好的产率从易于获得的起始原料合成各种菲啶。
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