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年龄作为不进行心肺复苏决策的一个因素:一项基于多中心盲法模拟的研究。

Age as a factor in do not attempt cardiopulmonary resuscitation decisions: a multicentre blinded simulation-based study.

作者信息

Moore Nicholas A, Wiggins Natasha, Adams Joe

机构信息

The Royal London Hospital, London, UK

Palliative Care Department, Princess Alice Hospice, Esher, UK.

出版信息

Palliat Med. 2015 Apr;29(4):380-5. doi: 10.1177/0269216314566838. Epub 2015 Feb 2.

Abstract

BACKGROUND

The European Resuscitation Council Guidelines recognise that there is a lack of direct evidence for the effect of age on outcome following cardiopulmonary resuscitation.

AIM

To determine the role that advancing age plays in the decision by clinicians to complete a do not attempt cardiopulmonary resuscitation order based on perceived futility.

DESIGN

A questionnaire-based trial. Clinicians were randomly assigned to receive one of two versions of a patient case, varying in age but otherwise identical (90 years vs 60 years). Participants were asked to decide whether a do not attempt cardiopulmonary resuscitation form should be completed based on perceived futility for a single patient case. Rates of do not attempt cardiopulmonary resuscitation order were compared between groups.

PARTICIPANTS

Consultant physicians, surgeons and anaesthetists from 12 district general hospitals in England.

RESULTS

In total, 291 questionnaires were returned. Overall, clinicians were significantly more likely to complete a do not attempt cardiopulmonary resuscitation form for a 90-year-old patient than a 60-year-old patient, when all other factors are equal (67.7% vs 7.4%, p < 0.001). This finding was consistent across speciality and experience level of the consultant. Surgeons were found to be significantly less likely to complete a do not attempt cardiopulmonary resuscitation order in the 90-year-old patient compared to other consultants (46.4% vs 74.1%, p < 0.001). Anaesthetists were more likely than other consultants to complete a do not attempt cardiopulmonary resuscitation order in the 60-year-old patient (17.8% vs 4.3%, p < 0.05).

CONCLUSION

Age is a highly significant independent factor in a clinicians' decision to withhold cardiopulmonary resuscitation. We highlight a potential gap between current practice and supporting evidence base.

摘要

背景

欧洲复苏委员会指南认识到,关于年龄对心肺复苏后预后影响的直接证据不足。

目的

确定高龄在临床医生基于认为复苏无效而决定开具不予心肺复苏医嘱方面所起的作用。

设计

一项基于问卷调查的试验。临床医生被随机分配接受两个版本患者病例中的一个,病例年龄不同但其他方面相同(90岁与60岁)。要求参与者根据对单个患者病例的无效认知,决定是否应开具不予心肺复苏表格。比较两组之间不予心肺复苏医嘱的开具率。

参与者

来自英格兰12家地区综合医院的顾问医师、外科医生和麻醉师。

结果

共返回291份问卷。总体而言,在所有其他因素相同的情况下,临床医生为90岁患者开具不予心肺复苏表格的可能性显著高于60岁患者(67.7%对7.4%,p<0.001)。这一发现在所涉专业及顾问的经验水平方面均一致。与其他顾问相比,外科医生为90岁患者开具不予心肺复苏医嘱的可能性显著更低(46.4%对74.1%,p<0.001)。麻醉师为60岁患者开具不予心肺复苏医嘱的可能性高于其他顾问(17.8%对4.3%,p<0.05)。

结论

年龄是临床医生决定放弃心肺复苏的一个非常重要的独立因素。我们强调了当前实践与支持性证据基础之间的潜在差距。

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