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短暂性角膜水肿是单纯性白内障手术后人工晶状体性黄斑囊样水肿的一个预测因素。

Transient corneal edema is a predictive factor for pseudophakic cystoid macular edema after uncomplicated cataract surgery.

作者信息

Do Jae Rock, Oh Jong-Hyun, Chuck Roy S, Park Choul Yong

机构信息

Department of Ophthalmology, Dongguk University Ilsan Hospital, Goyang, Korea.

Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Korean J Ophthalmol. 2015 Feb;29(1):14-22. doi: 10.3341/kjo.2015.29.1.14. Epub 2015 Jan 22.

Abstract

PURPOSE

To report transient corneal edema after phacoemulsification as a predictive factor for the development of pseudophakic cystoid macular edema (PCME).

METHODS

A total of 150 eyes from 150 patients (59 men and 91 women; mean age, 68.0 ± 10.15 years) were analyzed using spectral domain optical coherence tomography 1 week and 5 weeks after routine phacoemulsification cataract surgery. Transient corneal edema detected 1 week after surgery was analyzed to reveal any significant relationship with the development of PCME 5 weeks after surgery.

RESULTS

Transient corneal edema developed in 17 (11.3%) of 150 eyes 1 week after surgery. A history of diabetes mellitus was significantly associated with development of transient corneal edema (odds ratio [OR], 4.04; 95% confidence interval [CI], 1.41 to 11.54; p = 0.011). Both diabetes mellitus and transient corneal edema were significantly associated with PCME development 5 weeks after surgery (OR, 4.58; 95% CI, 1.56 to 13.43; p = 0.007; and OR, 6.71; CI, 2.05 to 21.95; p = 0.003, respectively). In the 8 eyes with both diabetes mellitus and transient corneal edema, 4 (50%) developed PCME 5 weeks after surgery.

CONCLUSIONS

Transient corneal edema detected 1 week after routine cataract surgery is a predictive factor for development of PCME. Close postoperative observation and intervention is recommended in patients with transient corneal edema.

摘要

目的

报告白内障超声乳化术后的短暂性角膜水肿作为人工晶状体性黄斑囊样水肿(PCME)发生的预测因素。

方法

对150例患者(59例男性和91例女性;平均年龄68.0±10.15岁)的150只眼在常规白内障超声乳化手术后1周和5周使用光谱域光学相干断层扫描进行分析。分析术后1周检测到的短暂性角膜水肿,以揭示其与术后5周PCME发生之间的任何显著关系。

结果

150只眼中有17只(11.3%)在术后1周出现短暂性角膜水肿。糖尿病病史与短暂性角膜水肿的发生显著相关(比值比[OR],4.04;95%置信区间[CI],1.41至11.54;p = 0.011)。糖尿病和短暂性角膜水肿均与术后5周PCME的发生显著相关(OR分别为4.58;95% CI,1.56至13.43;p = 0.007;以及OR为6.71;CI为2.05至21.95;p = 0.003)。在8例同时患有糖尿病和短暂性角膜水肿的眼中,4只(50%)在术后5周发生了PCME。

结论

常规白内障手术后1周检测到的短暂性角膜水肿是PCME发生的预测因素。建议对出现短暂性角膜水肿的患者进行密切的术后观察和干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/4309864/9641dd6b8ef7/kjo-29-14-g001.jpg

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