Minderaa R B, Stroink H, Blom W, Gunning W B, van Hemel J O
Ned Tijdschr Geneeskd. 1989 Feb 4;133(5):225-9.
In children with infantile autism or atypical pervasive developmental disorders somatic aspects play an important role. A review is presented of important hereditary, pre-, peri- and neonatal factors, findings at neurological examination, specific medical disorders and neurochemical and neurophysiological findings. Results of the medical examination of 15 children with autistic or atypical developmental disorders are presented. It is concluded that extensive medical examination of these children is indicated: in 8 out of 15 children a clinically relevant chromosomal, neurological or biochemical disorder could be detected.
在患有婴儿自闭症或非典型广泛性发育障碍的儿童中，躯体方面起着重要作用。本文综述了重要的遗传、产前、围产期和新生儿期因素、神经学检查结果、特定的医学病症以及神经化学和神经生理学发现。文中呈现了对15名患有自闭症或非典型发育障碍儿童的医学检查结果。得出的结论是，对这些儿童进行全面的医学检查是必要的：在15名儿童中有8名可检测出具有临床相关性的染色体、神经学或生化病症。
