• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Using Surveillance Data to Assess the HIV Tipping Point in the United States.利用监测数据评估美国的艾滋病毒转折点。
J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):e82-4. doi: 10.1097/QAI.0000000000000564.
2
Treatment. Only a third of individuals with HIV in U.S. have virus under control.
AIDS Policy Law. 2015 Feb;30(3):1, 4.
3
HIV surveillance, public health, and clinical medicine--will the walls come tumbling down?艾滋病病毒监测、公共卫生与临床医学——壁垒会轰然崩塌吗？
N Engl J Med. 2011 Aug 25;365(8):685-7. doi: 10.1056/NEJMp1107294.
4
Resistance to antiretroviral drugs: a threat to the prevention and treatment of pediatric HIV infection.对抗逆转录病毒药物的耐药性：对儿童HIV感染预防和治疗的威胁。
J Infect Dis. 2007 May 15;195(10):1393-5. doi: 10.1086/513880. Epub 2007 Apr 5.
5
Lessons from the 11th conference on retroviruses and opportunistic infections.第十一届逆转录病毒与机会性感染会议的经验教训。
AIDS Read. 2004 Apr;14(4):151-3.
6
Potential savings by reduced CD4 monitoring in stable patients with HIV receiving antiretroviral therapy.接受抗逆转录病毒治疗的HIV稳定患者减少CD4监测所带来的潜在节省。
JAMA Intern Med. 2013 Oct 14;173(18):1746-8. doi: 10.1001/jamainternmed.2013.9329.
7
Detecting spatial clusters of HIV and hepatitis coinfections.检测 HIV 和肝炎合并感染的空间聚集性。
PLoS One. 2018 Sep 18;13(9):e0203674. doi: 10.1371/journal.pone.0203674. eCollection 2018.
8
HIV testing, staging, and evaluation.艾滋病毒检测、分期及评估。
Infect Dis Clin North Am. 2014 Sep;28(3):339-53. doi: 10.1016/j.idc.2014.06.002.
9
Differences in human immunodeficiency virus care and treatment among subpopulations in the United States.美国各亚人群中的人类免疫缺陷病毒护理和治疗差异。
JAMA Intern Med. 2013 Jul 22;173(14):1337-44. doi: 10.1001/jamainternmed.2013.6841.
10
Comorbidities in Persons With HIV: The Lingering Challenge.艾滋病毒感染者的合并症：持续存在的挑战。
JAMA. 2020 Jan 7;323(1):19-20. doi: 10.1001/jama.2019.19775.

引用本文的文献

1
Assessing the utility of the tipping point ratio to monitor HIV treatment programmes in the era of universal access to ART.评估临界点比率在普及抗逆转录病毒治疗时代监测艾滋病治疗项目的效用。
Infect Dis Model. 2018 Mar 14;3:85-96. doi: 10.1016/j.idm.2018.03.005. eCollection 2018.

本文引用的文献

1
Trends in diagnoses of HIV infection in the United States, 2002-2011.2002 - 2011年美国HIV感染诊断趋势。
JAMA. 2014;312(4):432-4. doi: 10.1001/jama.2014.8534.
2
Estimating per-act HIV transmission risk: a systematic review.估计单次行为的HIV传播风险：一项系统评价。
AIDS. 2014 Jun 19;28(10):1509-19. doi: 10.1097/QAD.0000000000000298.
3
Disparities in HIV transmission risk among HIV-infected black and white men who have sex with men, United States, 2009.2009 年美国感染 HIV 的男同性恋者中，黑人和白人男性之间 HIV 传播风险的差异。
AIDS. 2014 Jan 2;28(1):105-14. doi: 10.1097/QAD.0000000000000021.
4
Differences in human immunodeficiency virus care and treatment among subpopulations in the United States.美国各亚人群中的人类免疫缺陷病毒护理和治疗差异。
JAMA Intern Med. 2013 Jul 22;173(14):1337-44. doi: 10.1001/jamainternmed.2013.6841.
5
High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa.高抗逆转录病毒治疗（ART）覆盖率与南非夸祖鲁-纳塔尔省农村地区艾滋病毒感染风险下降相关。
Science. 2013 Feb 22;339(6122):966-71. doi: 10.1126/science.1228160.
6
Prevention of HIV-1 infection with early antiretroviral therapy.早期抗逆转录病毒疗法预防 HIV-1 感染。
N Engl J Med. 2011 Aug 11;365(6):493-505. doi: 10.1056/NEJMoa1105243. Epub 2011 Jul 18.
7
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study.加拿大不列颠哥伦比亚省高效抗逆转录病毒治疗覆盖率、人群病毒载量与每年新增 HIV 诊断病例的关联：一项基于人群的研究。
Lancet. 2010 Aug 14;376(9740):532-9. doi: 10.1016/S0140-6736(10)60936-1. Epub 2010 Jul 16.
8
Decreases in community viral load are accompanied by reductions in new HIV infections in San Francisco.社区病毒载量的下降伴随着旧金山新的 HIV 感染的减少。
PLoS One. 2010 Jun 10;5(6):e11068. doi: 10.1371/journal.pone.0011068.
9
Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model.将普遍自愿艾滋病毒检测与立即进行抗逆转录病毒治疗作为消除艾滋病毒传播的策略：一个数学模型
Lancet. 2009 Jan 3;373(9657):48-57. doi: 10.1016/S0140-6736(08)61697-9. Epub 2008 Nov 27.

利用监测数据评估美国的艾滋病毒转折点。

Using Surveillance Data to Assess the HIV Tipping Point in the United States.

作者信息

Hall H Irene, Espinoza Lorena, Harris Shericka, Tang Tian, Mermin Jonathan

机构信息

*Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA †ICF International, Atlanta, GA ‡National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Atlanta Georgia.

出版信息

J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):e82-4. doi: 10.1097/QAI.0000000000000564.

DOI:10.1097/QAI.0000000000000564
PMID:25647526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8689566/
Abstract

Tipping point ratios <1 with fewer annual HIV infections than persons initiating HIV treatment indicate favorable epidemiologic situations to reduce HIV incidence. Using HIV surveillance data on persons newly diagnosed and virally suppressed in 2011 for 10 US jurisdictions, the tipping point ratio was 1.5 overall and ranged from 0.6 to 2.7. This indicates some jurisdictions have reached the point where the number of persons achieving viral suppression outpaces the number diagnosed with HIV. Expansion of treatment for all persons diagnosed with HIV as indicated in current treatment guidelines will benefit people living with HIV as well as prevention.

摘要

临界点比率小于1且年度新增艾滋病毒感染人数少于开始接受艾滋病毒治疗的人数，表明在降低艾滋病毒发病率方面存在有利的流行病学情况。利用美国10个司法管辖区2011年新诊断出并实现病毒抑制的人员的艾滋病毒监测数据，总体临界点比率为1.5，范围在0.6至2.7之间。这表明一些司法管辖区已达到实现病毒抑制的人数超过新诊断出艾滋病毒的人数的阶段。按照当前治疗指南的要求扩大对所有诊断出艾滋病毒的人员的治疗，将使艾滋病毒感染者受益，同时也有利于预防工作。