Paul E, Bödeker R H
Zentrum für Dermatologie und Andrologie-Hautklinik-am Klinikum, Justus-Liebig-Universität Giessen, W Germany.
Ann Allergy. 1989 Apr;62(4):318-20.
Forty patients with chronic urticaria were treated with terfenadine or astemizole in a randomized double-blind study. The intensity of the symptoms was quantified and documented daily by the patients. Both antihistamines had a clear effect on the intensity of the pruritus and the severity of the wheals. Neither astemizole nor terfenatine produced any sedative side effects.
在一项随机双盲研究中，40名慢性荨麻疹患者接受了特非那定或阿司咪唑治疗。患者每天对症状强度进行量化并记录。两种抗组胺药对瘙痒强度和风团严重程度均有明显效果。阿司咪唑和特非那定均未产生任何镇静副作用。
