Tavee Jinny O, Levin Kerry H
Continuum (Minneap Minn). 2015 Feb;21(1 Spinal Cord Disorders):52-66. doi: 10.1212/01.CON.0000461084.71618.35.
This article reviews the current evaluation and treatment of patients with myelopathy due to cervical spondylotic disease and other structural disorders of the spine.
In patients with cervical spondylotic myelopathy, symptom duration, severity at baseline, and possibly age have been identified as key prognostic markers of clinical course and postsurgical outcome. Other potential markers include specific MRI and EMG findings. The diagnosis and monitoring of syringomyelia is enhanced by the addition of phase contrast MRI, which evaluates CSF flow dynamics. Flexion MRI is helpful in establishing the diagnosis of Hirayama disease, which is now attributed to a tightened dural sac that is displaced anteriorly on neck flexion, compressing the cord.
Advances in neuroimaging along with new insights into the pathophysiology of structural spine diseases can help guide clinical decision making and optimize patient outcomes.
本文综述了因颈椎病和其他脊柱结构紊乱导致脊髓病患者的当前评估和治疗方法。
在颈椎病性脊髓病患者中,症状持续时间、基线严重程度以及可能的年龄已被确定为临床病程和术后结果的关键预后指标。其他潜在指标包括特定的MRI和肌电图检查结果。通过增加评估脑脊液流动动力学的相位对比MRI可加强对脊髓空洞症的诊断和监测。屈曲位MRI有助于诊断平山病,该病现在被认为是由于硬脊膜囊在颈部屈曲时向前移位并收紧,压迫脊髓所致。
神经影像学的进展以及对脊柱结构疾病病理生理学的新认识有助于指导临床决策并优化患者治疗结果。