Strollo S E, Caserotti P, Ward R E, Glynn N W, Goodpaster B H, Strotmeyer E S
Elsa S. Strotmeyer, PhD, MPH, Department of Epidemiology, University of Pittsburgh, 130 North Bellefield Avenue, Room 515, Pittsburgh, PA 15213, USA. Telephone: 412-383-1293 Fax: 412-383-1308
J Nutr Health Aging. 2015 Feb;19(2):240-8. doi: 10.1007/s12603-014-0528-y.
This review investigates the relationship between leg muscle power and the chronic conditions of osteoarthritis, diabetes mellitus, and cardiovascular disease among older adults. Current literature assessing the impact of chronic disease on leg power has not yet been comprehensively characterized. Importantly, individuals with these conditions have shown improved leg power with training.
A search was performed using PubMed to identify original studies published in English from January 1998 to August 2013. Leg power studies, among older adults ≥ 50 years of age, which assessed associations with osteoarthritis, diabetes mellitus, and/or cardiovascular disease were selected. Studies concerning post-surgery rehabilitation, case studies, and articles that did not measure primary results were excluded.
Sixteen studies met inclusion criteria, addressing osteoarthritis (n=5), diabetes mellitus (n=5), and cardiovascular disease (n=6). Studies generally supported associations of lower leg power among older adults with chronic disease, although small sample sizes, cross-sectional data, homogenous populations, varied disease definitions, and inconsistent leg power methods limited conclusions.
Studies suggest that osteoarthritis, diabetes mellitus, and cardiovascular disease are associated with lower leg power compared to older adults without these conditions. These studies are limited, however, by the heterogeneity in study populations and a lack of standardized measurements of leg power. Future larger studies of more diverse older adults with well-defined chronic disease using standard measures of leg power and interventions to improve leg power in these older adults with chronic disease are needed.
本综述调查老年人腿部肌肉力量与骨关节炎、糖尿病和心血管疾病等慢性病之间的关系。目前评估慢性病对腿部力量影响的文献尚未得到全面描述。重要的是,患有这些疾病的个体通过训练已显示出腿部力量有所改善。
使用PubMed进行检索,以识别1998年1月至2013年8月以英文发表的原创研究。选择了年龄≥50岁的老年人中评估与骨关节炎、糖尿病和/或心血管疾病相关性的腿部力量研究。排除了有关术后康复的研究、案例研究以及未测量主要结果的文章。
16项研究符合纳入标准,涉及骨关节炎(n = 5)、糖尿病(n = 5)和心血管疾病(n = 6)。研究总体上支持患有慢性病的老年人腿部力量较低的相关性,尽管样本量小、横断面数据、同质人群、疾病定义不同以及腿部力量测量方法不一致限制了结论。
研究表明,与没有这些疾病的老年人相比,骨关节炎、糖尿病和心血管疾病与较低的腿部力量相关。然而,这些研究受到研究人群异质性以及缺乏腿部力量标准化测量的限制。未来需要对更多样化的患有明确慢性病的老年人进行更大规模的研究,使用腿部力量的标准测量方法以及针对这些患有慢性病的老年人改善腿部力量的干预措施。