Suppr超能文献

伴有变异的滤泡型甲状腺乳头状癌

Follicular variant papillary thyroid carcinoma with a twist.

作者信息

Nwaeze Obinna, Obidike Stephen, Mullen Dorinda, Aftab Fuad

机构信息

Surgery Department, Mallow General Hospital, Mallow, Cork, Ireland.

Histopathology Department, Cork University Hospital, Cork, Ireland.

出版信息

Int J Surg Case Rep. 2015;8C:107-10. doi: 10.1016/j.ijscr.2015.01.019. Epub 2015 Jan 14.

Abstract

BACKGROUND

We report an adnexal lesion, which turned out to be a metastasis to the scalp from a left sided follicular variant papillary thyroid cancer. The patient has had history of right multi-nodular goiter 10 years prior to presentation.

CASE PRESENTATION

A 75-year old lady presented with a cutaneous lesion about 1 year post left total thyroidectomy for FVPTC. She underwent surgical excision of the lesion and histology revealed it to be metastases from a thyroid carcinoma.

DISCUSSION

Cutaneous metastases from thyroid carcinomas are relatively uncommon in clinical practice. A worldwide literature review reveals that follicular carcinoma has a greater preponderance than papillary carcinoma for cutaneous metastasis and that the majority of skin metastases from either papillary or follicular thyroid cancer are localized to the head and neck, with the scalp as the commonest site.

CONCLUSION

Skin metastasis from papillary and follicular thyroid carcinoma is an uncommon occurrence and these lesions should be differentiated from primary skin tumors. They are very important to recognize as early recognition can lead to accurate and prompt diagnosis leading to timely treatment. The scalp has been found to be the commonest site of cutaneous metastasis that may appear benign.

摘要

背景

我们报告一例附件区病变,结果是左侧滤泡型乳头状甲状腺癌转移至头皮。患者在就诊前10年有右叶多发结节性甲状腺肿病史。

病例介绍

一名75岁女性在因滤泡型乳头状甲状腺癌行左侧甲状腺全切术后约1年出现皮肤病变。她接受了病变的手术切除,组织学检查显示为甲状腺癌转移。

讨论

甲状腺癌的皮肤转移在临床实践中相对少见。一项全球文献综述显示,滤泡癌比乳头状癌更容易发生皮肤转移,并且乳头状或滤泡状甲状腺癌的大多数皮肤转移局限于头颈部,头皮是最常见的部位。

结论

乳头状和滤泡状甲状腺癌的皮肤转移并不常见,这些病变应与原发性皮肤肿瘤相鉴别。认识到它们非常重要,因为早期识别可导致准确、及时的诊断,从而实现及时治疗。头皮已被发现是可能表现为良性的皮肤转移最常见的部位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e038/4353927/b299cbcbc446/gr1.jpg

相似文献

1
Follicular variant papillary thyroid carcinoma with a twist.
Int J Surg Case Rep. 2015;8C:107-10. doi: 10.1016/j.ijscr.2015.01.019. Epub 2015 Jan 14.
3
[Cutaneous metastases from follicular thyroid cancer].
Presse Med. 2000 Sep 30;29(28):1557-8.
5
Clinical presentations and outcomes of surgical treatment of follicular variant of the papillary thyroid carcinomas.
Jpn J Clin Oncol. 2006 Nov;36(11):688-93. doi: 10.1093/jjco/hyl093. Epub 2006 Sep 25.
6
Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A review on Surgical Treatment.
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):6384-6390. doi: 10.1007/s12070-022-03107-z. Epub 2022 Jul 23.
8
An unusual case of papillary carcinoma of the thyroid with cutaneous and breast metastases only.
Eur J Endocrinol. 1997 Sep;137(3):267-9. doi: 10.1530/eje.0.1370267.
9
[Follicular thyroid carcinoma: metastasis to unusual skin locations].
Presse Med. 2005 Sep 24;34(16 Pt 1):1145-6. doi: 10.1016/s0755-4982(05)84140-5.
10
Solitary liver metastasis from follicular variant papillary thyroid carcinoma: A case report and literature review.
Int J Surg Case Rep. 2015;6C:146-9. doi: 10.1016/j.ijscr.2014.11.080. Epub 2014 Dec 12.

引用本文的文献

2
Multi-Omics and Management of Follicular Carcinoma of the Thyroid.
Biomedicines. 2023 Apr 19;11(4):1217. doi: 10.3390/biomedicines11041217.
3
An H- Mutated Skin Metastasis as First Occurrence in a Case of Follicular Thyroid Carcinoma.
Front Endocrinol (Lausanne). 2019 Jul 31;10:513. doi: 10.3389/fendo.2019.00513. eCollection 2019.
4
Rare behavior of follicular variant of papillary thyroid cancer.
Clin Case Rep. 2017 Sep 18;5(11):1789-1792. doi: 10.1002/ccr3.1177. eCollection 2017 Nov.

本文引用的文献

1
Uncommon metastases from differentiated thyroid carcinoma.
Hell J Nucl Med. 2012 Sep-Dec;15(3):233-40. doi: 10.1967/s002449910059. Epub 2012 Oct 25.
2
A 64 year-old female with scalp metastasis of papillary thyroid cancer.
Indian J Endocrinol Metab. 2011 Jul;15(Suppl 2):S136-7. doi: 10.4103/2230-8210.83353.
3
Cutaneous metastasis from follicular variant of papillary thyroid carcinoma: a case diagnosed on cytology.
Indian J Pathol Microbiol. 2008 Jan-Mar;51(1):91-3. doi: 10.4103/0377-4929.40414.
4
5
Cutaneous manifestations of thyroid cancer: a report of four cases and review of the literature.
J Clin Pathol. 2004 Apr;57(4):435-8. doi: 10.1136/jcp.2003.012922.
8
Thyroid carcinoma metastatic to the skin: a cutaneous manifestation of a widely disseminated malignancy.
J Am Acad Dermatol. 1997 Apr;36(4):531-7. doi: 10.1016/s0190-9622(97)70239-1.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验