Cariou B, Charbonnel B, Heymann M F, Bridji B
Service de Médecine nucléaire, Hôtel Dieu, Nantes.
Presse Med. 2000 Sep 30;29(28):1557-8.
Cutaneous metastases from differentiated thyroid carcinoma are rare: only 41 cases have been reported in the literature.
A 57-year-old woman underwent total thyroidectomy for a poor differentiated follicular thyroid carcinoma, with involvement of sternum and pulmonary metastases. Despite iodine-131 ablative therapy (> 1 Ci) she developed a skin metastasis of the scalp 9 years after the initial surgery. She died of widely metastatic thyroid carcinoma.
Follicular carcinoma has a greater preponderance than papillary carcinoma for cutaneous metastases. The majority of skin metastases are localized to the head and neck. The development of a cutaneous metastasis is commonly associated with metastasis to other distant tissues and is followed by a deteriorating course and eventual death resulting from malignancy.
分化型甲状腺癌的皮肤转移罕见：文献中仅报道过41例。
一名57岁女性因低分化滤泡状甲状腺癌接受了全甲状腺切除术，伴有胸骨受累和肺转移。尽管进行了碘-131消融治疗（>1居里），但在初次手术后9年，她出现了头皮皮肤转移。她死于广泛转移的甲状腺癌。
滤泡状癌比乳头状癌更易发生皮肤转移。大多数皮肤转移局限于头颈部。皮肤转移的发生通常与其他远处组织的转移相关，随后病情恶化，最终因恶性肿瘤死亡。
