Tanaka Shinji, Kashida Hiroshi, Saito Yutaka, Yahagi Naohisa, Yamano Hiroo, Saito Shoichi, Hisabe Takashi, Yao Takashi, Watanabe Masahiko, Yoshida Masahiro, Kudo Shin-Ei, Tsuruta Osamu, Sugihara Ken-Ichi, Watanabe Toshiaki, Saitoh Yusuke, Igarashi Masahiro, Toyonaga Takashi, Ajioka Yoichi, Ichinose Masao, Matsui Toshiyuki, Sugita Akira, Sugano Kentaro, Fujimoto Kazuma, Tajiri Hisao
Japan Gastroenterological Endoscopy Society, Tokyo, Japan.
Japanese Society for Cancer of the Colon and Rectum, Tokyo, Japan.
Dig Endosc. 2015 May;27(4):417-434. doi: 10.1111/den.12456. Epub 2015 Mar 5.
Colorectal endoscopic submucosal dissection (ESD) has become common in recent years. Suitable lesions for endoscopic treatment include not only early colorectal carcinomas but also many types of precarcinomatous adenomas. It is important to establish practical guidelines in which the preoperative diagnosis of colorectal neoplasia and the selection of endoscopic treatment procedures are properly outlined, and to ensure that the actual endoscopic treatment is useful and safe in general hospitals when carried out in accordance with the guidelines. In cooperation with the Japanese Society for Cancer of the Colon and Rectum, the Japanese Society of Coloproctology, and the Japanese Society of Gastroenterology, the Japan Gastroenterological Endoscopy Society has recently compiled a set of colorectal ESD/endoscopic mucosal resection (EMR) guidelines using evidence-based methods. The guidelines focus on the diagnostic and therapeutic strategies and caveat before, during, and after ESD/EMR and, in this regard, exclude the specific procedures, types and proper use of instruments, devices, and drugs. Although eight areas, ranging from indication to pathology, were originally planned for inclusion in these guidelines, evidence was scarce in each area. Therefore, grades of recommendation were determined largely through expert consensus in these areas.
近年来,结直肠内镜黏膜下剥离术(ESD)已变得很常见。适合内镜治疗的病变不仅包括早期结直肠癌,还包括多种癌前腺瘤。制定切实可行的指南很重要,其中应恰当概述结直肠肿瘤的术前诊断和内镜治疗程序的选择,并确保在综合医院按照指南进行实际内镜治疗时既有用又安全。日本胃肠内镜学会最近与日本结直肠癌学会、日本大肠肛门病学会以及日本胃肠病学会合作,采用循证方法编制了一套结直肠ESD/内镜黏膜切除术(EMR)指南。这些指南重点关注ESD/EMR术前、术中和术后的诊断和治疗策略及注意事项,在这方面,不包括具体的操作步骤、器械、设备和药物的类型及正确使用方法。尽管最初计划在这些指南中纳入从适应证到病理等八个领域,但每个领域的证据都很少。因此,这些领域的推荐等级很大程度上是通过专家共识确定的。