• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Prosomes discriminate between mRNA of adenovirus-infected and uninfected HeLa cells.

作者信息

Horsch A, Martins de Sa C, Dineva B, Spindler E, Schmid H P

机构信息

Biologisches Institut, Universität Stuttgart, FRG.

出版信息

FEBS Lett. 1989 Mar 27;246(1-2):131-6. doi: 10.1016/0014-5793(89)80268-6.

DOI:10.1016/0014-5793(89)80268-6
PMID:2565252
Abstract

Prosomes are small cytoplasmic RNP complexes associated with repressed mRNA. In in vitro translation, they discriminate between the mRNA of adenovirus-infected HeLa cells and those of uninfected cells grown under normal conditions. Prosomes as well as their RNA constituents interact much more strongly with poly(A)+ mRNA of infected cells and inhibit their translation in vitro preferentially. A possible role of prosomes in the differential regulation of translation is discussed.

摘要

相似文献

1
Prosomes discriminate between mRNA of adenovirus-infected and uninfected HeLa cells.
FEBS Lett. 1989 Mar 27;246(1-2):131-6. doi: 10.1016/0014-5793(89)80268-6.
2
Prosomes are involved in the repression of viral mRNA.前体微粒体参与病毒信使核糖核酸的抑制过程。
Z Naturforsch C Biosci. 1985 May-Jun;40(5-6):449-50. doi: 10.1515/znc-1985-5-627.
3
Selection of prosomes and prosomal RNA by immobilized viral RNAs.通过固定化病毒RNA选择前体小体和前体小体RNA
FEBS Lett. 1990 Sep 3;269(2):336-40. doi: 10.1016/0014-5793(90)81188-t.
4
Inhibition of exogenous RNA-dependent protein synthesis by a low-molecular-weight RNA from nuclear ribonucleoprotein particles of adenovirus-infected HeLa cells.来自腺病毒感染的HeLa细胞核核糖核蛋白颗粒的低分子量RNA对外源RNA依赖性蛋白质合成的抑制作用。
Biochem Biophys Res Commun. 1978 May 15;82(1):384-91. doi: 10.1016/0006-291x(78)90621-6.
5
Prosomes. Ubiquity and inter-species structural variation.原核小体。普遍性及种间结构变异。
J Mol Biol. 1986 Feb 20;187(4):479-93. doi: 10.1016/0022-2836(86)90328-1.
6
Specific poly-A-binding protein of 76,000 molecular weight in polyribosomes is not present on poly A of free cytoplasmic mRNP.多核糖体中分子量为76,000的特异性聚腺苷酸结合蛋白不存在于游离细胞质信使核糖核蛋白颗粒的聚腺苷酸上。
Nature. 1977 Nov 10;270(5633):189-91. doi: 10.1038/270189a0.
7
Nuclear and cytoplasmic adenovirus RNA. Differences between 5'-terminal of messenger and non-messenger transcripts.细胞核和细胞质中的腺病毒RNA。信使RNA与非信使RNA转录本5'末端的差异。
J Mol Biol. 1976 Mar 5;101(3):379-96. doi: 10.1016/0022-2836(76)90154-6.
8
Shut-off of actin biosynthesis in adenovirus serotype-2-infected cells.腺病毒2型感染细胞中肌动蛋白生物合成的关闭。
J Mol Biol. 1984 Jun 5;175(4):453-68. doi: 10.1016/0022-2836(84)90179-7.
9
Comparisons of proteins associated with duck-globin mRNA and its polyadenylated segment in polyribosomal and repressed free messenger ribonucleoprotein complexes.鸭珠蛋白信使核糖核酸及其多聚腺苷酸化片段在多核糖体和受抑制的游离信使核糖核蛋白复合体中相关蛋白质的比较。
Eur J Biochem. 1981 Feb;114(2):179-93. doi: 10.1111/j.1432-1033.1981.tb05135.x.
10
A new type of prosome-like particle, composed of small cytoplasmic RNA and multimers of a 21-kDa protein, inhibits protein synthesis in vitro.一种新型的类核小体颗粒，由小细胞质RNA和一种21 kDa蛋白质的多聚体组成，可在体外抑制蛋白质合成。
Eur J Biochem. 1987 Dec 30;170(1-2):23-33. doi: 10.1111/j.1432-1033.1987.tb13663.x.

引用本文的文献

1
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.酚-甲苯抽提法纯化交联的 RNA-蛋白质复合物。
Nat Commun. 2019 Mar 1;10(1):990. doi: 10.1038/s41467-019-08942-3.
2
Substrate affinity and substrate specificity of proteasomes with RNase activity.具有核糖核酸酶活性的蛋白酶体的底物亲和力和底物特异性。
Mol Biol Rep. 2003 Mar;30(1):1-7. doi: 10.1023/a:1022261925117.
3
Relationships between proteasomes and viral gene products.蛋白酶体与病毒基因产物之间的关系。
Mol Biol Rep. 1999 Apr;26(1-2):113-7. doi: 10.1023/a:1006982023524.
4
Expression of a proteasome alpha-type subunit gene during tobacco development and senescence.蛋白酶体α型亚基基因在烟草发育和衰老过程中的表达
Plant Mol Biol. 1999 Jan;39(2):325-33. doi: 10.1023/a:1006102110889.
5
Involvement of proteasomal subunits zeta and iota in RNA degradation.蛋白酶体亚基ζ和ι在RNA降解中的作用。
Biochem J. 1997 Aug 15;326 ( Pt 1)(Pt 1):93-8. doi: 10.1042/bj3260093.
6
Proteasome (prosome) associated endonuclease activity.蛋白酶体（原核小体）相关的核酸内切酶活性。
Mol Biol Rep. 1997 Mar;24(1-2):113-7. doi: 10.1023/a:1006886911852.
7
Phylogenic relationships of the amino acid sequences of prosome (proteasome, MCP) subunits.前体小体（蛋白酶体、MCP）亚基氨基酸序列的系统发育关系。
Mol Gen Genet. 1994 Dec 15;245(6):769-80. doi: 10.1007/BF00297284.
8
Proteasomes (prosomes) inhibit the translation of tobacco mosaic virus RNA by preventing the formation of initiation complexes.蛋白酶体（原核小体）通过阻止起始复合物的形成来抑制烟草花叶病毒RNA的翻译。
Mol Biol Rep. 1994;20(2):57-61. doi: 10.1007/BF00996354.
9
The prosomal RNA-binding protein p27K is a member of the alpha-type human prosomal gene family.前体RNA结合蛋白p27K是α型人类前体基因家族的成员。
Mol Gen Genet. 1993 Feb;237(1-2):193-205. doi: 10.1007/BF00282801.
10
Relationships between proteasomes and RNA.蛋白酶体与RNA之间的关系。
Mol Biol Rep. 1995;21(1):43-7. doi: 10.1007/BF00990969.