血细胞入胞作用——综述
Emperipolesis - a review.
作者信息
Rastogi Varun, Sharma Rachna, Misra Satya Ranjan, Yadav Lalita, Sharma Vandana
机构信息
Reader, Department of Oral & Maxillofacial Pathology, Kalka Dental College , Meerut, Uttar Pradesh, India .
Senior Lecturer, Department of Oral & Maxillofacial Pathology, Seema Dental College & Hospital , Rishikesh Uttrakhand, India .
出版信息
J Clin Diagn Res. 2014 Dec;8(12):ZM01-2. doi: 10.7860/JCDR/2014/10361.5299. Epub 2014 Dec 5.
Abstract
Emperipolesis is an uncommon biological process, in which a cell penetrates another living cell. Unlike in phagocytosis where the engulfed cell is killed by lysosomal enzymes of the macrophage, the cell exists as viable cell within another in emperipolesis and can exit at any time without any structural or functional abnormalities for either of them. This process can either be physiological or pathological and may be a pathognomonic feature of certain diseases. Histiocytes and Megakaryocytes are involved in Emperipolesis normally but tumour giant cells in Hodgkin's disease and Rosai-Dorfman disease are pathologic conditions in which this process is seen. We report a mini review as this process is rare and not much reported in the literature.
摘要
细胞内吞是一种罕见的生物学过程，即一个细胞穿透另一个活细胞。与吞噬作用不同，在吞噬作用中被吞噬的细胞会被巨噬细胞的溶酶体酶杀死，而在细胞内吞过程中，该细胞在另一个细胞内以活细胞形式存在，并且可以随时离开，两者均不会出现任何结构或功能异常。这个过程既可以是生理性的，也可以是病理性的，可能是某些疾病的特征性表现。组织细胞和巨核细胞通常参与细胞内吞，但霍奇金病和罗萨伊-多夫曼病中的肿瘤巨细胞是出现此过程的病理情况。由于这个过程很罕见且在文献中报道不多，我们在此进行简要综述。
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