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一家儿科急诊科中三种性传播感染的患病率。

Prevalence of 3 sexually transmitted infections in a pediatric emergency department.

作者信息

Miller Melissa K, Dowd M Denise, Harrison Christopher J, Mollen Cynthia J, Selvarangan Rangaraj, Humiston Sharon G

机构信息

From the Divisions of *Emergency and Urgent Care and †Infectious Disease, Department of Pediatrics, Children's Mercy Hospitals and Clinics, Kansas City, MO; ‡Division of Emergency Medicine, Children's Hospital of Philadelphia; and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; and §Department of Pathology and Laboratory Medicine, Children's Mercy Hospitals and Clinics, Kansas City, MO.

出版信息

Pediatr Emerg Care. 2015 Feb;31(2):107-12. doi: 10.1097/PEC.0000000000000284.

Abstract

OBJECTIVE

This study aimed to determine the prevalence of Chlamydia trachomatis, Neisseria gonorrheae, and Trichomonas vaginalis and to describe factors associated with sexually transmitted infection (STI) in a pediatric emergency department (ED).

METHODS

Adolescents aged 14 to 19 years presenting to a Midwestern pediatric ED were asked to provide urine for STI testing and complete a survey about previous sexual activity (PSA), high-risk behaviors, demographics, and visit reason (reproductive: genitourinary complaints, abdominal pain, or a female with vomiting). Comparisons between subgroups were analyzed using Χ test.

RESULTS

Among 200 subjects (64% of approached), mean age was 15.6 years; 63% were female. Eleven subjects (6%; 95% confidence interval, 2.3-8.7) tested positive for 1 or more STIs: 10 for C. trachomatis (one denied PSA), 3 for T. vaginalis (all coinfected with C. trachomatis), and 1 for N. gonorrheae. Half reported PSA; of these, 71% reported 1 or more high-risk behaviors, most commonly first sex before the age of 15 years (51%) and no condom at last sex (42%). Among those with PSA and nonreproductive visit (n = 73), 11.0% had 1 or more STIs (95% confidence interval, 3.4-18.1). Two factors were associated with greater likelihood of positive STI test result, namely, reporting PSA versus no PSA (10% vs 1%, P = 0.005) and last sex within 1 month or less versus more than 1 month (20% vs 0%, P = 0.001). In this sample, none of the following characteristics were associated with STI: insurance, race, high-risk behaviors, age, or ED visit reason.

CONCLUSIONS

Approximately 1 in 10 sexually active adolescent ED patients without reproductive complaints had 1 or more STIs. This suggests the need for strategies to increase STI testing for this population.

摘要

目的

本研究旨在确定沙眼衣原体、淋病奈瑟菌和阴道毛滴虫的感染率,并描述儿科急诊科(ED)中性传播感染(STI)的相关因素。

方法

邀请到中西部儿科急诊科就诊的14至19岁青少年提供尿液进行性传播感染检测,并完成一份关于既往性活动(PSA)、高危行为、人口统计学特征和就诊原因(生殖系统相关:泌尿生殖系统不适、腹痛或有呕吐症状的女性)的调查问卷。亚组间比较采用卡方检验进行分析。

结果

在200名受试者(占邀请人数的64%)中,平均年龄为15.6岁;63%为女性。11名受试者(6%;95%置信区间,2.3 - 8.7)1种或多种性传播感染检测呈阳性:10例沙眼衣原体阳性(1例否认有性活动),3例阴道毛滴虫阳性(均与沙眼衣原体合并感染),1例淋病奈瑟菌阳性。一半受试者报告有性活动;其中,71%报告有1种或多种高危行为,最常见的是15岁之前首次性行为(51%)和最近一次性行为未使用避孕套(42%)。在有性活动且非生殖系统相关就诊的受试者中(n = 73),11.0%有1种或多种性传播感染(95%置信区间,3.4 - 18.1)。两个因素与性传播感染检测结果呈阳性的可能性增加相关,即报告有性活动与未报告有性活动(10%对1%,P = 0.005)以及最近一次性行为在1个月内或更短时间与超过1个月(20%对0%,P = 0.001)。在该样本中,以下特征均与性传播感染无关:保险类型、种族、高危行为、年龄或急诊科就诊原因。

结论

约十分之一无生殖系统不适症状的性活跃青少年急诊患者有一种或多种性传播感染。这表明需要制定策略来增加对该人群的性传播感染检测。

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