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智利青少年和青年中沙眼衣原体、淋病奈瑟菌及阴道毛滴虫感染的患病率

Prevalence of Chlamydia Trachomatis, Neisseria Gonorrhoeae, and Trichomonas Vaginalis Infection in Chilean Adolescents and Young Adults.

作者信息

Huneeus Andrea, Schilling Andrea, Fernandez Mario I

机构信息

Department of Obstetrics and Gynecology, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago, Chile.

Department of Obstetrics and Gynecology, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago, Chile.

出版信息

J Pediatr Adolesc Gynecol. 2018 Aug;31(4):411-415. doi: 10.1016/j.jpag.2018.01.003. Epub 2018 Feb 1.

DOI:10.1016/j.jpag.2018.01.003
PMID:29409759
Abstract

STUDY OBJECTIVE

To determine the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis infection in sexually active Chilean adolescents and young adults. A comparative analysis was performed between genders to identify demographic, clinical, and sexual behavior characteristics to predict the occurrence of C trachomatis.

DESIGN

Analytical observational study.

SETTING

Santiago, Chile.

PARTICIPANTS

Two hundred eighty-six sexually active volunteers aged 24 years or younger (171 female and 115 male); 82.9% (237/286) of them were classified as having high socioeconomic status.

INTERVENTIONS

Confidential survey and self-collected samples (urine for men and vaginal swabs for women).

MAIN OUTCOME MEASURES

Prevalence, demographic characteristics, symptoms, and sexual behavior characteristics.

RESULTS

The prevalence rate of C trachomatis was 8.7% (10/115) in men and 8.8% (15/171) in women (P = .58). N gonorrhoeae was detected in 1 subject, whereas no T vaginalis cases were detected. In multivariate analysis, having some college education was protective (odds ratio [OR], 0.28; 95% confidence interval [CI], 0.09-0.89), whereas having a higher number of sexual partners was a risk factor (OR, 1.19; 95% CI, 1.1-1.3) for C trachomatis infection. The latter was also predicted by postcoital bleeding (OR, 4.6; 95% CI, 1.30-16.23) in the female model.

CONCLUSION

C trachomatis infection rates were similar between both genders. Protective characteristics for the occurrence of this infection were having some college education, lower number of sexual partners, and if female, the absence of postcoital bleeding. This study highlights the importance of C trachomatis screening among the Chilean affluent population younger than 25 years. However, further studies are needed in a more diverse and representative sample to recommend universal screening in Chilean adolescents and young adults.

摘要

研究目的

确定智利性活跃青少年和青年中沙眼衣原体、淋病奈瑟菌及阴道毛滴虫感染的患病率。对不同性别进行比较分析,以确定人口统计学、临床和性行为特征,从而预测沙眼衣原体感染的发生情况。

设计

分析性观察研究。

地点

智利圣地亚哥。

参与者

286名24岁及以下的性活跃志愿者(女性171名,男性115名);其中82.9%(237/286)被归类为社会经济地位较高。

干预措施

保密调查及自行采集样本(男性为尿液,女性为阴道拭子)。

主要观察指标

患病率、人口统计学特征、症状及性行为特征。

结果

男性沙眼衣原体患病率为8.7%(10/115),女性为8.8%(15/171)(P = 0.58)。检测到1例淋病奈瑟菌感染,未检测到阴道毛滴虫感染病例。多因素分析显示,接受过一些大学教育具有保护作用(比值比[OR],0.28;95%置信区间[CI],0.09 - 0.89),而性伴侣数量较多是沙眼衣原体感染的危险因素(OR,1.19;95% CI,1.1 - 1.3)。在女性模型中,性交后出血也可预测沙眼衣原体感染(OR,4.6;95% CI,1.30 - 16.23)。

结论

沙眼衣原体感染率在两性间相似。该感染发生的保护因素包括接受过一些大学教育、性伴侣数量较少,以及女性无性交后出血情况。本研究强调了在智利25岁以下富裕人群中进行沙眼衣原体筛查的重要性。然而,需要在更多样化且具代表性的样本中开展进一步研究,以建议在智利青少年和青年中进行普遍筛查。

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