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肯尼亚蒙巴萨青少年和年轻女性的性传播感染筛查:可行性、流行率及相关因素。

Screening for Sexually Transmitted Infections in Adolescent Girls and Young Women in Mombasa, Kenya: Feasibility, Prevalence, and Correlates.

机构信息

From the *Department of Medicine, University of Washington, Seattle, WA; †University of Nairobi Institute of Tropical & Infectious Disease (UNITID), Nairobi; ‡Department of Environment and Health Sciences, Technical University of Mombasa, Mombasa; §School of Nursing Sciences, University of Nairobi, Nairobi; ¶Mombasa County Department of Health, Mombasa, Kenya; ∥Department of Global Health, **Biostatistics, University of Washington; ††Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center; and ‡‡Department of Epidemiology, University of Washington, Seattle, WA.

出版信息

Sex Transm Dis. 2017 Dec;44(12):725-731. doi: 10.1097/OLQ.0000000000000674.

Abstract

INTRODUCTION

As adolescents and young women become sexually active, they are at risk of adverse reproductive health outcomes including sexually transmitted infections (STIs). We assessed feasibility and acceptability of STI screening among 15- to 24-year-old women in Mombasa, Kenya.

METHODS

After sensitization activities, participants were recruited from 3 high schools and 1 university. Study staff conducted informational sessions. Students interested in participating were given consent forms to take home, and invited to visit our clinic for STI screening. During clinic visits, participants completed a self-administered questionnaire and provided a urine specimen for STI testing using a nucleic acid amplification test.

RESULTS

Between August 2014 and March 2015, 463 high school and 165 university students collected consent forms. Of these, 293 (63%) from high schools versus 158 (95%) from university attended clinic for STI screening (P < 0.001). Of the 150 (33%) who reported any history of insertive vaginal sex, 78 (52.0%) reported condom use at the last sex act, 31 (20.7%) reported using modern nonbarrier contraceptive methods, and 37 (24.7%) reported not using any contraception at the last sex act. Twenty-six (5.8%) participants were diagnosed with STIs (7 [1.6%] Neisseria gonorrhoeae, 16 [3.6%] Chlamydia trachomatis, 3 [0.7%] Trichomonas vaginalis). In multivariable analyses, reporting receptive vaginal sex without a condom was associated with having a laboratory confirmed STI (odds ratio, 6.21; 95% confidence interval, 1.72-22.28).

CONCLUSIONS

These findings support the need for reproductive health interventions to reduce the risk of STIs in a population of adolescent girls and young women in East Africa.

摘要

简介

随着青少年和年轻女性开始性行为,她们面临着包括性传播感染(STI)在内的不良生殖健康后果的风险。我们评估了肯尼亚蒙巴萨市 15 至 24 岁女性的 STI 筛查的可行性和可接受性。

方法

在宣传活动之后,我们从 3 所高中和 1 所大学招募参与者。研究人员举办了信息会议。有兴趣参与的学生领取了带回家的同意书,并邀请他们到我们的诊所进行 STI 筛查。在诊所就诊时,参与者完成了一份自我管理的问卷,并提供了尿液样本,使用核酸扩增试验进行 STI 检测。

结果

2014 年 8 月至 2015 年 3 月,463 名高中生和 165 名大学生领取了同意书。其中,293 名(63%)高中生和 158 名(95%)大学生参加了诊所的 STI 筛查(P < 0.001)。在报告有过插入性阴道性行为的 150 名参与者中,78 名(52.0%)报告在最近一次性行为中使用了避孕套,31 名(20.7%)报告使用了现代非屏障避孕方法,37 名(24.7%)报告在最近一次性行为中未使用任何避孕措施。26 名(5.8%)参与者被诊断患有 STI(7 名[1.6%]淋病奈瑟菌,16 名[3.6%]沙眼衣原体,3 名[0.7%]阴道毛滴虫)。在多变量分析中,报告没有使用避孕套的接受性阴道性行为与实验室确认的 STI 相关(比值比,6.21;95%置信区间,1.72-22.28)。

结论

这些发现支持在东非的青少年和年轻女性人群中开展生殖健康干预措施,以降低 STI 的风险。

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