Australian Centre for Research on Separation Science (ACROSS), School of Medicine, University of Tasmania, Australia; KIST-Europe, Saarbrücken, Germany.
Electrophoresis. 2015 Mar;36(5):644-5. doi: 10.1002/elps.201500044.
Lab on a Chip technology offers the possibility to extract chemical information from a complex sample in a simple, automated way without the need for a laboratory setting. In the health care sector, this chemical information could be used as a diagnostic tool for example to inform dosing. In this issue, the research underpinning a family of electrophoresis-based point-of-care devices for self-testing of ionic analytes in various sample matrices is described [Electrophoresis 2015, 36, 712-721.]. Hardware, software, and methodological chances made to improve the overall analytical performance in terms of accuracy, precision, detection limit, and reliability are discussed. In addition to the main focus of lithium monitoring, new applications including the use of the platform for veterinary purposes, sodium, and for creatinine measurements are included.
芯片实验室技术提供了一种可能，无需实验室环境，即可简单、自动地从复杂样本中提取化学信息。在医疗保健领域，这些化学信息可以用作诊断工具，例如，用于告知剂量。在本期中，描述了一系列基于电泳的即时检测设备的研究基础，这些设备用于在各种样本基质中自我检测离子分析物[电泳，2015 年，36 卷，712-721]。讨论了为提高准确性、精密度、检测限和可靠性等整体分析性能而做出的硬件、软件和方法学方面的改进。除了锂监测的主要关注点外，还包括该平台在兽医用途、钠和肌酐测量方面的新应用。
