短肽超分子水凝胶的手性对蛋白质结晶生成的影响。
Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis.
作者信息
Conejero-Muriel Mayte, Gavira José A, Pineda-Molina Estela, Belsom Adam, Bradley Mark, Moral Mónica, García-López Durán Juan de Dios, Luque González Angélica, Díaz-Mochón Juan J, Contreras-Montoya Rafael, Martínez-Peragón Ángela, Cuerva Juan M, Álvarez de Cienfuegos Luis
机构信息
Laboratorio de Estudios Cristalográficos, Instituto Andaluz de Ciencias de la Tierra (CSIC-UGR), Av. de las Palmeras 4, 18100 Armilla, Granada, Spain.
出版信息
Chem Commun (Camb). 2015 Mar 4;51(18):3862-5. doi: 10.1039/c4cc09024a.
For the first time the influence of the chirality of the gel fibers in protein crystallogenesis has been studied. Enantiomeric hydrogels 1 and 2 were tested with model proteins lysozyme and glucose isomerase and a formamidase extracted from B. cereus. Crystallization behaviour and crystal quality of these proteins in both hydrogels are presented and compared.
首次研究了凝胶纤维的手性在蛋白质结晶过程中的影响。用模型蛋白溶菌酶、葡萄糖异构酶以及从蜡状芽孢杆菌中提取的甲酰胺酶对映体水凝胶1和2进行了测试。展示并比较了这些蛋白质在两种水凝胶中的结晶行为和晶体质量。
Zotero 插件