Mellinghoff H, Diefenbach C, Arhelger S, Buzello W
Institut für Anästhesiologie, Universität Köln.
Anasth Intensivther Notfallmed. 1989 Feb;24(1):57-9.
The recording of the evoked twitch tension has been the established reference method to quantitate neuromuscular blockade. The evoked compound electromyogram has been introduced later as a clinically more convenient alternative. We compared both methods in 20 patients in whom cumulative dose response curves of vecuronium and the time constants of weaning neuromuscular blockade were determined. The evoked twitch tension was slightly more sensitive in detecting residual neuromuscular blockade than the EMG. No significant differences between the two methods were found in the cumulative 90% blocking dose, the duration of block and the recovery time (25%-75%). These results are in agreement with communications of previous authors using different nondepolarizing muscle relaxants. In the absence of abnormal conditions such as neuromuscular disorders and hypothermia, recording of evoked electromyography is a clinically satisfactory method to quantitate neuromuscular blockade.
诱发抽搐张力的记录一直是定量神经肌肉阻滞的既定参考方法。诱发复合肌电图后来作为一种临床上更方便的替代方法被引入。我们在20例患者中比较了这两种方法，这些患者测定了维库溴铵的累积剂量反应曲线和神经肌肉阻滞撤机的时间常数。诱发抽搐张力在检测残余神经肌肉阻滞方面比肌电图略敏感。在累积90%阻滞剂量、阻滞持续时间和恢复时间（25%-75%）方面，两种方法未发现显著差异。这些结果与先前使用不同非去极化肌松药的作者的报道一致。在没有神经肌肉疾病和体温过低等异常情况时，诱发肌电图记录是定量神经肌肉阻滞的一种临床上令人满意的方法。
