Mortier E, Rolly G
Dept. of Anesthesia, Univ. Hospital, Ghent, Belgium.
Acta Anaesthesiol Belg. 1989;40(2):123-6.
The Datex Relaxograph is a neuromuscular transmission monitor, which measures the degree of neuromuscular blockade during anesthesia. In order to evaluate the reliability of the Relaxograph, results, obtained with this apparatus, were compared with simultaneous mechanical measurements obtained with the Myograph 2000 (Biometer). Although there was a good correlation between the two throughout the study, a shift towards mechanical responses was observed in all cases. Subsequently, the Relaxograph was used to evaluate atracurium and vecuronium when given accordingly to the priming principle. Results show that neither drug offers major clinical advantages over the other. In a third study, a new bolus-constant infusion regimen of atracurium was evaluated. Results show that it produces a predictable and stable neuromuscular blockade.
Datex Relaxograph是一种神经肌肉传递监测仪，用于测量麻醉期间神经肌肉阻滞的程度。为了评估Relaxograph的可靠性，将该仪器获得的结果与使用Myograph 2000（生物测量仪）同时进行的机械测量结果进行了比较。尽管在整个研究过程中两者之间存在良好的相关性，但在所有情况下均观察到向机械反应的偏移。随后，根据预注原则使用Relaxograph评估阿曲库铵和维库溴铵。结果表明，两种药物均未显示出比另一种药物具有更大的临床优势。在第三项研究中，评估了一种新的阿曲库铵单次静脉注射-持续静脉输注方案。结果表明，它能产生可预测且稳定的神经肌肉阻滞。
